Spectrophotometric method
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In this study, the simultaneous determination of Co, Cd, Ni, Cu, and Pb was carried out as a color complex with 4-(2-pyridylazo) resorcinol in an aqueous solution under the assesting of machine learning. A partial least-squares multivariate linear regression and artificial neuron network for the analysis of mixtures of metals were developed. MATLAB is a powerful software machine learning program that was used to support matrix calculations and displays.
8p visergeyne 18-06-2024 0 0 Download
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Simple, rapid, sensitive, precise and specific UV spectrophotometric method for the determination of isoniazid (INH) in active pharmaceutical ingredient were developed and validated. A simple double beam UV spectrophotometric method has been studied with different parameters such as linearity, precision, repeatability, accuracy as per ICH guidelines.
6p vibego 02-02-2024 1 0 Download
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A new spectrophotometric method was established for the determination of nimodipine (NMD) in pharmaceutical formulations. This method is based on the formation of a yellow ion-pair complex between the reduced nimodipine and bromothymol blue (BTB) in an acidic medium.
12p viengels 25-08-2023 6 3 Download
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Pancreatic lipase is one of the safest targets of anti-obesity drugs. To date, orlistat is the only pancreatic lipase inhibitor approved for the long-term treatment of obesity. Therefore, there is an elevated need to find new drugs for this disease. Determining the factors affecting the test to evaluate pancreatic lipase inhibitory activity in order to build a standard assay procedure is necessary. This will make it much easier for researchers to find novel compounds that inhibit the enzyme.
6p viwolverine 07-07-2023 7 1 Download
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The present work is a development simple, sensitive and selective spectrophotometric method for determination of amoxicillin in dosage forms. Based on the diazotization of aniline and sulfanilic acid with nitrite ion in acidic medium to colorless diazonium ion, which subsequently coupled with amoxicillin to form a colored azo dye in the alkaline medium.
7p vidoctorstrange 06-05-2023 6 2 Download
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The QSPR modeling is popularly used in many fields as in silico approach for predicting properties of chemical compounds based on the relationships between the structural characteristics and the properties.
11p viargus 03-03-2023 2 2 Download
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In this study, we developed a simple, fast, and inexpensive method to analyze cefotaxime in powder for injection based on the charge transfer reaction with the DDQ reagent in acetonitrile solvent.
7p viargus 03-03-2023 8 2 Download
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In this paper, we have prepared peripherally tetra-({6-[3-(diethylamino)phenoxy]hexyl}oxy substituted cobalt(II), copper(II), manganese(III) phthalocyanines (3, 4, 5) and their water-soluble derivatives (3a, 4a, 5a). Then, in vitro α-glucosidase and cholinesterases inhibitory actions of the water-soluble 3a, 4a, 5a were examined using spectrophotometric methods. 4a had the highest inhibitory effects among the tested compounds against α-glucosidase due to IC50 values. 4a and 5a had 40 fold higher inhibitory effects than the positive control.
11p lyhuyenthu 31-01-2023 7 2 Download
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A new spectrophotometric method for determinating trace amounts of fluoride has been introduced in this article. The principle of the method is based on the reaction of fluoride with a complex of aluminum ion and xylenol orange reagent (Al-XO).
5p vichristinelagarde 04-07-2022 8 1 Download
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The aim of the study "Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy" was to develop derivative, Fourier- and wavelet-based UV spectrophotometric methods for the simultaneous determination of cefoperazone and sulbactam in powders for injection using Reversed Phase High Performance Liquid Chromatogram (RP-HPLC) as a reference method.
11p runordie3 27-06-2022 15 2 Download
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Simple and accurate spectrophotometric methods are presented for the determination of five 3-hydroxy-3- methylglutaryl coenzyme-A (HMG-CoA) reductase inhibitors (statins), namely atorvastatin, fluvastatin, pitavastatin, rosuvastatin, and simvastatin, in pharmaceutical preparations. The methods are based on the reaction of drugs as n-electron donor with 7,7,8,8-tetracyanoquinodimethane as π-acceptors to give highly colored complex species. All variables were studied in order to optimize the reaction conditions.
11p langthannam 29-12-2021 7 0 Download
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A new spectrophotometric method has been developed for determination of molybdenum using surfactantmediated liquid–liquid extraction. Molybdenum(V) obtained by ascorbic acid reduction in 2.5 M H2 SO4 reacted spontaneously with thiocyanate and cetyl trimethyl ammonium bromide (CTAB), forming an intense orange yellow complex that was extracted quantitatively into 1,2-dichloroethane and absorbed at 460 nm. The absorbance of the extract was found to be stable for more than 24 h.
10p langthannam 29-12-2021 9 0 Download
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A simple and efficient method for speciation and determination of iron in different water samples was developed. The method is based on ionic liquid ultrasound assisted dispersive liquid–liquid microextraction (IL-USADLLME) followed by spectrophotometric determination. Fe(II) is complexed with 2,4,6-tri(2’-pyridyl)-l,3,5-triazine (TPTZ), neutralized through ion pair formation with sodium dodecyl sulfate (SDS) and extracted into 1-hexyl-3- methylimidazolium hexafluorophosphate [C6MIM][PF6].
10p langthannam 29-12-2021 10 0 Download
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A novel method for the determination of mercury(II) is suggested. The procedure is based on the formation of an ion associate between the bromide complex of Hg(II) and Astrazon Red 6B dye and vortex-assisted liquid–liquid microextraction of the ion associate formed, with subsequent spectrophotometric detection. The variables that affect the procedure, such as pH, the concentration of ligand and dye, the type and volume of extraction solvent, and the rate and time of vortex mixing, were optimized.
9p langthannam 29-12-2021 6 0 Download
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This study reports 2 new simple derivatization-based dispersive liquid–liquid microextraction (DLLME) methods for spectrophotometric ultratrace determination of asulam and sulfide. 1-Naphthol (in the presence of nitrite) and N,N-diethyl-p-phenylenediamine (in the presence of Fe(III)) were used to derivatize asulam and sulfide, respectively. In the enrichment methods, the formed derivatives were preconcentrated into microdroplets of the in situ formed water insoluble ionic liquid (IL), 1-hexyl-3-methylimidazolium hexafluorophosphate.
15p langthannam 29-12-2021 11 0 Download
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Carmoisine (E122) is a synthetic azo dye that is generally used to give a red color to food products. In this work, a sensitive and simple method was developed for the determination of carmoisine based on cloud point extraction. To obtain the optimum conditions for the extraction efficiency of carmoisine, the effects of different analytical parameters such as H2 SO4 concentration, concentration of Triton X-114, and equilibrium temperature were studied. The calibration graph was linear between 0.05 and 5.
7p langthannam 29-12-2021 8 0 Download
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This work describes the synthesis of sebacic acid capped silver nanoparticles (SA-AgNPs) by the wet chemical method for the detection of L-Histidine in blood serum and urine samples. The synthesized SAAgNPs were characterized by several techniques.
8p meyerowitz 25-12-2021 4 0 Download
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Immediate preconcentration and spectrophotometric methods have been developed for the determination of trace amounts of cupric ion (Cu(II)) and nickel ion (Ni(II)) through a solid phase extraction with XAD-4-N,N’-bis- (salicylidene) cyclohexanediamine (XAD-4-SCHD) resin and a complex color reaction of the ions with 2,6-dimethylmorpholine dithiocarbamate (DMMDTC) in Triton X-100 media. A high preconcentration factor of 125 was achieved.
11p tudichquannguyet 29-11-2021 3 1 Download
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A simple and sensitive supramolecular solvent-based dispersive liquid–liquid microextraction method was described for the separation/preconcentration and spectrophotometric detection of rhodamine B. The microextraction method, which was realized at ambient temperature for the detection of rhodamine B, was carried out by using supramolecular solvents such as tetrahydrofuran and decanoic acid. The method was based on analyses of rhodamine B by using UV-Vis spectrophotometry at 558 nm.
8p tudichquannguyet 29-11-2021 10 1 Download
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An accurate, precise, and simple spectrophotometric method is proposed for the determination of the antithyroid drug carbimazole using ruthenium(III) chloride. This method is based on the formation at room temperature of a stable yellow-colored complex with λmax 370 nm. The method has a Beer’s law range of 7.81 to 1.95 × 10 2 µg mL−1, molar absorptivity coefficient ε = 1.519 × 103 L mol−1 cm−1, and correlation coefficient of 0.997. The metal:ligand (M:L) ratio of the complex was confirmed by the mole ratio and Job’s method of continuous variation, suggesting a 1:2 stoichiometry.
18p tudichquannguyet 29-11-2021 8 0 Download