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Development of spectrophotometric method for determination of amoxicillin by diazocoupling reaction in pharmaceutical formulations

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The present work is a development simple, sensitive and selective spectrophotometric method for determination of amoxicillin in dosage forms. Based on the diazotization of aniline and sulfanilic acid with nitrite ion in acidic medium to colorless diazonium ion, which subsequently coupled with amoxicillin to form a colored azo dye in the alkaline medium.

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Nội dung Text: Development of spectrophotometric method for determination of amoxicillin by diazocoupling reaction in pharmaceutical formulations

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