Surface interactions

Proprotein convertase subtilisin/kexin type 9 (PCSK9), the last member of the proprotein convertase family, functions as a classic regulator of low-density lipoprotein (LDL) by interacting with low-density lipoprotein receptor (LDLR). Recent studies have shown that PCSK9 can affect the occurrence and development of tumors and can be used as a novel therapeutic target. However, a comprehensive pan-cancer analysis of PCSK9 has yet to be conducted.

13p vishanshan 27-06-2024 1 1   Download

T cell immunoglobulin and mucin-domain containing-3 (TIM-3) is a cell surface molecule that was first discovered on T cells. However, recent studies revealed that it is also highly expressed in acute myeloid leukemia (AML) cells and it is related to AML progression. As, Glutamine appears to play a prominent role in malignant tumor progression, especially in their myeloid group, therefore, in this study we aimed to evaluate the relation between TIM-3/Galectin-9 axis and glutamine metabolism in two types of AML cell lines, HL-60 and THP-1.

15p vikoch 27-06-2024 3 1   Download

Part 2 of ebook "Engineering rock mechanics - Part 2: Illustrative worked examples" provides readers with contents including: Chapter 13 - Rock dynamics and time dependency; Chapter 14 - Rock mechanics interactions and rock engineering systems; Chapter 15 - Excavation principles; Chapter 16 - Rock reinforcement and rock support; Chapter 17 - Foundation and slope instability mechanisms; Chapter 18 - Design of surface excavations; Chapter 19 - Underground excavation instability mechanisms; Chapter 20 - Design of underground excavations;...

297p giangdongdinh 28-05-2024 2 2   Download

The aim of this study was to evaluate the biological activity of some pyridine derivatives (compounds 1 to 15) on perfusion pressure in an isolated rat heart model. Furthermore, theoretical interaction of pyridine derivatives with the M2 muscarinic receptor was determined using acetylcholine, AF-DX 116 and the 3uon protein as theoretical tools in a docking model.

11p dianmotminh02 03-05-2024 1 1   Download

In this study, a facile synthesis and grafting method is reported for tetradentate Cu(II) Schiff base complex onto the surface of graphene oxide (GO). The Schiff base Cu-complex was synthesized through the condensation reaction between 2,3-diamino pyridine and 2-hydroxy-1-naphthaldehyde, followed by the addition of Cu(II) ion to afford N2O2-Cu(II) complex.

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This review provided detail information about production, structure and properties of NC. The usage of NC as reinforcement materials for different types of biopolymers is presented in the review. The surface modification of NC for better dispersion and better interaction of NCs in polymer matrices, the mechanical and thermal properties of the NC biopolymer nanocomposites are discussed.

25p dianmotminh02 03-05-2024 1 1   Download

The F2B slab model weakens the oscillations and calculations on F2B model quickly converge. However, the F2B model leads to artificial narrowness of band gap. Besides, when the number of layers increases, surface energy obtained from all three slab models approaches similar values. In particular, values of surface energy from DFT calculations converge to the experimental range for all three slab models.

8p dianmotminh02 03-05-2024 5 2   Download

Ebook "Study of the peptide–peptide and peptide–protein interactions and their applications in cell imaging and nanoparticle surface modification" focuses on the study of interactions between protein and peptides and their potential applications in cell imaging and nanoparticle surface modification. Drawing inspiration from naturally occurring coiled-coil binding pairs, it proposes a novel covalent peptide tag and probe system, based on the concept of “affinity guided covalent conjugation.

103p tracanhphuonghoa1007 22-04-2024 3 3   Download

Ebook Computer graphics, C Version (2nd Ed) includes contents: Chapter 1 a survey of computer graphics, chapter 2 overview of graphics systems, chapter 3 output primitives, chapter 4 attributes of output primitives, chapter 5 two-dimensional geometric transformations, chapter 6 two-dimensional viewing, chapter 7 structures & hierarchical modeling, chapter 8 graphic user interfaces & interactive input methods, chapter 9 three dimensional concepts, chapter 10 three-dimensional object representations, chapter 11 three-dimensional geometric & modeling transformations, chapter 12 three-dimension...

662p longtimenosee05 31-03-2024 2 0   Download

Ebook "From single molecules to nanoscopically structured materials" principle relied on the defined functionalization of macromolecules and macromolecular assemblies. The basic idea was to chemically encode the building blocks, permitting better control of structure formation. The placement of ionic or hydrogen-bonding groups into well-defined positions, the definition of amphiphilic “patches” and the creation of directed as well as non-directed interactions have led to novel aggregate topologies in solution as well as on surfaces.

293p tudohanhtau1006 29-03-2024 2 1   Download

Ebook "Orthogonal supramolecular interaction motifs for functional monolayer architectures" describes a combination of orthogonal supramolecular interactions for the design of functional monolayer architectures on surfaces, that can be used as chemical and biosensors in a wide range of applications. The term “orthogonal supramolecular interactions” refers to non-covalent interactions that do not influence each other's assembly properties.

115p coduathanh1122 27-03-2024 1 1   Download

Ebook "Protein-Protein interactions (Topics in Medicinal chemistry, Volume 8)" surveys the field of inhibitors of the MDM2/p53 interaction, which essentially began with the high-profile disclosure of Nutlins, and quickly and steadily grew through programs at a number of pharmaceutical companies. The MDM2/p53 interaction constitutes a paradigm example of a relatively large, hydrophobic interaction surface for which lead compounds can easily be found.

276p coduathanh1122 27-03-2024 5 1   Download

Ebook "Steric effects in the chemisorption of vibrationally excited methane on nickel" uses a molecular beam and infrared laser techniques to prepare methane in excited rovibrational states. The excited methane molecules are aligned relative to the target nickel surface. Bruce describes the discovery and exploration of a previously unknown steric effect in the dissociation reaction between a vibrationally excited methane molecule and a nickel crystal.

185p coduathanh1122 27-03-2024 2 1   Download

Ebook "Ionic liquid bulk and interface properties: Electronic interaction, molecular orientation and growth characteristics" focuses on issues related to thin IL coatings, in particular concerning new catalytic concepts such as the supported ionic liquid phase (SILP) and solid catalyst with ionic liquid layer (SCILL) systems. Till Cremer presents a number of fundamental contributions to the new field of "Ionic Liquid Surface and Interface Science".

178p coduathanh1122 27-03-2024 3 1   Download

Ebook "Viral entry into host cells" for a virus to invade a host cell it needs to penetrate the physical barrier imposed by the plasma membrane. Viruses have evolved specialized surface proteins to meet this challenge. These proteins facilitate delivery of the viral genetic information into the host cell by either fusing the viral envelope with a host cell membrane or by forming membrane pores. Membrane fusion and pore formation critically depend on the engagement of host cell receptors and receptor choice is a key determinant of viral tropism.

213p cotieubac1004 15-03-2024 0 0   Download

Ebook "Nanomicrobiology: Physiological and environmental characteristics" is devoted to nanomicrobiology and the nanosystems of bacteria. The initial chapter discusses some of the controversies in the geochemical and biomedical fields associated with the reports of nanobacteria in the environment. Current knowledge of several internal and surface structures of bacteria is addressed in this book. Included are chapters discussing carboxysomes, S-layers, gliding motility of bacteria, and aggregation of iron to produce nano-magnetite.

188p manmanthanhla0201 26-02-2024 2 1   Download

In ebook "Complex macromolecular systems II (Advances in polymer science, Volume 228)" the combination and interplay of these well-balanced “internal fields” with “external fields” such as mechanical, electrical, magnetic, electromagnetic, and/or the interactions with surfaces are a powerful tool to create defect-free and perfectly ordered macromolecular structures on a macroscopic scale, leading to new material properties, processes, and applications.

221p manmanthanhla0201 26-02-2024 4 1   Download

Ebook "Generic and specific roles of saccharides at cell and bacteria surfaces: Revealed by specular and off-specular X-ray and neutron scattering" has led to the development of several new methods for extracting information on the structure and mechanics of saccharide-rendered biomembranes from the measured scattering signals. In fact, more is now known about the influence of the saccharide structure.

138p manmanthanhla0201 26-02-2024 1 1   Download

Ebook "Analytics of Protein–DNA interactions (Advances in biochemical engineering/biotechnology, Volume 104)" focuses on the fascinating possibilities that emerged during the last years to study protein–DNA interactions in vitro. As an essential part of transcriptional activity during development and in tumorgenesis a separate chapter describing the analysis of DNA modification especially methylation of cytosines at their carbon-5 position was included.

212p manmanthanhla0201 27-02-2024 4 2   Download

Ebook "Food emulsifiers and their applications (Second edition)" has focused on the design and application of emulsifiers as versatile food ingredients. The second edition has updated and expanded applications, from both theoretical and practical perspectives. The first three chapters describe design, synthesis, analysis, and commercial preparation of emulsifiers. Synergistic and antagonistic interactions with other food ingredients, such as carbohydrates, proteins, and water, are discussed in the next three chapters.

433p manmanthanhla0201 27-02-2024 2 1   Download