Surface interactions

In recent years, the understanding of processes on material surfaces has drawn considerable interest from scientists. The adsorption stage is important for further insights into surface interactions and photocatalytic reactions. In this study, we use density functional theory computations to investigate the adsorption of sulfamethoxazole (SMX) molecules on the rutile-TiO2 (001) surface (r-TiO2 ).

8p viyoko 01-10-2024 3 1   Download

The question sustained throughout the project, and developed into four key principal research aims or foci, framing my research approach and helping to define the field covered. These concerned: abstracting musical basslines into an environmental domain; articulating building materials through vibration; composing for a tactile sensation bodily experience; understanding the dialogue between hearing and sensation, and how felt and audible aspects affect awareness and perception of each other.

112p runthenight07 01-03-2023 8 3   Download

To study relation of molecular structural changing between polypropylene microcomposite system and the particle fillers with varies phase interactions by using solid-state NMR(ssNMR) spectra.Therein,emphasizing the molecular flexibility on mechanical properties of materials.

22p capheviahe27 23-02-2021 12 2   Download

The mechanism of corrosion inhibition was explored and supplemented by adsorption and surface morphological studies. Quantum mechanical investigations on corrosion behaviour of compounds were also conducted and satisfying correlation was noticed between the results of corrosion measurement methods and quantum mechanical evaluations.

12p tocectocec 25-05-2020 20 2   Download

In this paper, to enhance the safety of these lines, response of a buried 56-inch diameter high pressure natural gas pipeline to a surface blast was numerically investigated. Besides, the effects of: i) explosive mass, ii) pipeline thickness, iii) burial depth and iv) concrete protective layer on pipeline deformation were parametrically studied.

20p tohitohi 19-05-2020 34 1   Download

This article deals with the thermoelastic interaction in a three-dimensional homogeneous and isotropic viscoelastic medium under the Dual-phase-lag model of generalized thermoelasticity. The resulting non-dimensional coupled equations are applied to a specific problem of a half-space whose surface is traction-free and is subjected to a time-dependent thermal shock.

14p tohitohi 19-05-2020 13 1   Download

In the course of trying to understand the pathogenesis of leishmaniasis in relation to extracellular matrix (ECM) elements, laminin, a major ECM protein, has been found to bind saturably and with high affinity to a 67-kDa cell surface protein of Leishmania donovani. This interaction involves a single class of binding sites, which are ionic in nature, conformation-dependent and possibly involves sulfhydryls. Binding activity was significantly enhanced by Zn2+, an effect possibly mediated through Cys-rich zinc finger-like sequences on laminin....

8p system191 01-06-2013 44 4   Download

The interaction of blood coagulation factor X and its Gla-containing fragments with negatively charged phospholipid membranes composed of 25 mol% phosphatidylserine (PtdSer) and 75 mol% phosphatidylcholine (PtdCho) was studied by surface plasmon resonance. The binding to 100 mol% PtdCho membranes was negligible. The calcium dependence in the membrane binding was evaluated for intact bovine factor X (factor X) and the fragment containing the Gla-domain and the N-terminal EGF (epidermal growth factor)-like domain, Gla–EGFN, from factor X....

6p system191 01-06-2013 34 4   Download

Cys341 of carboxypeptidase Y, which constitutes one side of the solvent-accessible surface of the S1 binding pocket, was replaced with Gly, Ser, Asp, Val, Phe or His by site-directed mutagenesis. Kinetic analysis, using Cbz-dipeptide substrates, revealed that polar amino acids at the 341 position increased Km whereas hydrophobic amino acids in this position tended to decrease Km.

6p system191 01-06-2013 40 4   Download

The interaction between the c11ring and thececomplex, forming the rotor of theIlyobacter tartaricus ATP synthase, was probed by surface plasmon resonance spectroscopy andin vitro reconstitution analysis. The results pro-vide, for the first time, a direct and quantitative assessment of the stability of the rotor. The data indicated very tight binding between the c11ring and the cecomplex, with an apparent Kd value of approximately 7.4 nm.

13p research12 29-04-2013 47 3   Download

In this paper we address the problem of extracting features relevant for predicting protein±protein interaction sites from the three-dimensional structures of protein complexes. Our approach is based on information about evolutionary con-servation and surface disposition. We implement a neural network based system, which uses a cross validation proce-dure and allows the correct detection of 73% of the residues involved in protein interactions in a selected database comprising 226 heterodimers.

6p research12 29-04-2013 32 3   Download

Hepatopoietin (HPO) is a novel human hepatotrophic growth factor. Recently, we demonstrated that the extra-cellular ligand form of HPO can stimulate proliferation of hepatic cells via its specific receptor, which is on the surface of these cells.Also, the intracellular formofHPOpotentiates the transcriptional factor AP-1. Intriguingly, a variety of HPO complexes with different molecular masses were detected in hepatocytes.

6p research12 23-04-2013 26 5   Download

Different pathways of bilayer disruption by the structurally related antimicrobial peptides cecropin B, B1 and B3, revealed by surface plasma resonance analysis of immobi-lized liposomes, differential scanning calorimetryof peptide– large unilamellar vesicle interactions, and light microscopic analysis of peptide-treated giant unilamellar vesicles, have been identified inthis study.

10p tumor12 20-04-2013 41 3   Download

Soybean 4-kDa peptide, a hormone-like peptide, is a ligand for the 43-kDaprotein in legumes that functions as aprotein kinase and controls cell proliferation and differentiation. As this peptide stimulates proteinkinase activity, the interaction between the 4-kDa peptide (leginsulin) and the 43-kDa protein is considered important for signal transduction. However, the mechanism of interaction between the 4-kDa peptide and the 43-kDa protein is not clearly understood.

10p fptmusic 16-04-2013 37 3   Download

Several microbial pathogens have been reported to interact with glycosaminoglycans (GAGs) on cell surfaces and in the extracellularmatrix. Herewe demonstrate thatM protein, a major surface-expressed virulence factor of the human bac-terial pathogen, Streptococcus pyogenes, mediates binding to various forms of GAGs. Hence, S. pyogenesstrains expressing a large number of different types of M proteins bound to dermatan sulfate (DS), highly sulfated fractions of heparan sulfate (HS) and heparin, whereas strains deficient in M protein surface expression failed to interact with these GAGs. ...

9p fptmusic 16-04-2013 49 6   Download

Novel antithrombin molecules were identified from the ixodidae tick, Haemaphysalis longicornis. These molecules, named madanin 1 and 2, are 7-kDa proteins and show no significant similarities to any previously identified proteins. Assays using human plasma showed that madanin 1 and 2 dose-dependently prolonged both activated partial throm-boplastin time and prothrombin time, indicating that they inhibit both the intrinsic and extrinsic pathways. Direct binding assay by surface plasmon resonance measurement demonstrated that madanin 1 and 2 specifically interacted with thrombin....

9p fptmusic 16-04-2013 50 3   Download

Thrombomodulin (TM) slows down the interaction rate between thrombin and plasminogen activator inhibitor 1 (PAI-1). We now show that the 12-fold reduced inhibition rate in the presence ofTM does not result from an altered distribution between PAI-1 cleavage and irreversible com-plex formation. Surface plasmon resonance (SPR) revealed an over 200-fold reduced affinity of TM for thrombin-VR1 tPA as compared to thrombin, demonstrating the importance ofthe VR1 loop in the interaction ofthrombin withbothTMandPAI-1....

10p fptmusic 16-04-2013 45 3   Download

A new baculovirus-based fluorescence resonance energy transfer (Bv-FRET) assay for measuringmultimerization of cell surface molecules in living cells is described. It has been demonstrated that gonadotropin-releasing hormone recep-tor (GnRH-R) was capable of forming oligomeric com-plexes in the plasma membrane under normal physiological conditions. The mouse gonadotropin-releasing hormone receptor GnRH-R was used to evaluate the efficiency and potential applications of this assay.

9p fptmusic 12-04-2013 61 4   Download

The enzymes pyruvate decarboxylase (E1) and dihydro-lipoyl dehydrogenase (E3) bind tightly but in a mutually exclusive manner to the peripheral subunit-binding domain (PSBD) of dihydrolipoyl acetyltransferase in the pyruvate dehydrogenase multienzyme complex of Bacillus stearo-thermophilus.

9p fptmusic 12-04-2013 45 2   Download

The membrane-tethered mucins are cell surface-associated dimeric or multi-meric molecules with extracellular, transmembrane and cytoplasmic por-tions, that arise from cleavage of the primary polypeptide chain. Following the first cleavage, which may be cotranslational, the subunits remain closely associated through undefined noncovalent interactions.

11p awards 06-04-2013 44 4   Download