The form module
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The aim of this thesis was to investigate and characterise the effect on electron dosimetry that localising different forms of bolus, both approximately tissue equivalent and non tissue equivalent, in a non conventional, although reproducible locations, (ie not on the phantom surface). A series of experiments were derived to compare the differences in beam characteristics between the recognised conventional method of locating bolus on the surface to that of bolus supported by the Low Melting point Attenuator (LMA) Electron insert.
238p runthenight07 01-03-2023 4 4 Download
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This research examines how parametric loudspeakers may be considered unique acousmatic musical instruments; how the parametric acoustic array (PAA) can potentially make new forms of music and listening experiences; and how PAA-design problems can be overcome. Interdisciplinary in nature, the study uses grounded theory and experimental music practice within a design research methodology. Theory emerges from data, in concert with analysis and framing that draws on areas such as electroacoustic music, spatial composition, acoustics, PAA science/theory, modulation theory, and medium theory.
177p runthenight04 02-02-2023 3 3 Download
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This research project will investigate how combining systems of tessellation1 , modularity2 and seriality3 can be utilised with a specific method of paper staining to explore visual pathways within an artwork. A serial system4 of modular tessellation will be implemented, whereby different “sets” of oil-and-pigment soaked paper modules will be constructed and formed into various configurations.
98p runordie3 06-07-2022 9 4 Download
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Mục tiêu nghiên cứu là xây dựng module mã hóa từ dữ liệu người dùng sang dữ liệu máy tính và module giải mã dữ liệu máy sang dữ liệu người dùng có ứng dụng mã vạch. Từ đó ta có thể quản lý điểm qua mã vạch. Xây dựng bài toán ứng dụng phần mềm nhập điểm bằng mã vạch hai chiều vào trường Cao đẳng Y tế Thái Nguyên. Tích hợp với phần mềm quản lý người học, cổng thông tin đào tạo, phần mềm quản lý thư viện. Mời các bạn cùng tham khảo!
62p heavysweetness 04-08-2021 40 5 Download
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Lập trình viên ERP cần chịu trách nhiệm về các đầu việc như: phát triển/tùy chỉnh các mô-đun và API OpenERP Odoo trong Python, phối hợp với các nhóm chức năng chéo để xác định, thiết kế và cung cấp các tính năng mới, mô hình hóa dữ liệu, mô-đun và phát triển báo cáo, duy trì và cải thiện các chức năng ERP hiện có trong sản xuất... Ngoài ra, các bạn có thể tham khảo thêm về công việc của các vị trí khác trong khối phòng Công nghệ thông tin - IT qua 1p lottexylitol 24-06-2019 123 7 Download
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Quản trị viên website cần chịu trách nhiệm về các công việc như: tối ưu hệ thống Website, quản lý Website & Backup dữ liệu hệ thống Website, chỉnh sửa các module sẵn có trên website theo yêu cầu, nhân bản các Website của hệ thống dựa trên source code sẵn có... Ngoài ra, các bạn có thể tham khảo thêm về công việc của các vị trí khác trong khối phòng Công nghệ thông tin - IT qua Bộ Tài Liệu Hệ Thống Mô Tả Công Việc Dành Cho Nhân Viên IT trên trang TaiLieu.VN.
2p lottexylitol 24-06-2019 69 7 Download
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Module 1: Overview of Microsoft ISA Server 2004. This module provides an introduction to ISA Server 2004. It introduces the core functionality provided by ISA Server 2004 and presents an overview of how ISA Server 2004 integrates with other security practices to form a defense-in-depth approach to network security. The module also describes the most common deployment scenarios for ISA Server 2004.
15p nomoney2 10-02-2017 53 3 Download
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Departamento de Bioquı´mica y Biologı´a Molecular y Celular, Facultad de Ciencias, Universidad de Zaragoza, Spain; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA Reduction potential determinations of K75E, E139K and E301A ferredoxin-NADP+ reductases provide valuable information concerning the factors that contribute to tune the flavin reduction potential. Thus, while E139 is not involved in such modulation, the K75 side-chain tunes the flavin potential by creating a defined environment that modulates the FAD conformation. ...
6p system191 01-06-2013 36 4 Download
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Haematopoiesis, the differentiation of haematopoietic stem cells and progenitors into various lineages, involves complex interactions of transcription factors that modulate the expression of downstream genes and mediate proliferation and differentiation signals. Commitment of pluripotent haematopoietic stem cells to the erythroid lineage induces erythropoiesis, the production of red blood cells. This process involves a concerted progression through an erythroid burst forming unit (BFU-E), an erythroid colony forming unit (CFU-E), proerythroblast and an erythroblast....
12p research12 01-06-2013 47 4 Download
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Light/dark modulation of the higher plant Calvin-cycle enzymes phosphoribulokinase (PRK) and NADP-depend-ent glyceraldehyde 3-phosphate dehydrogenase (NADP-GAPDH-A2B2) involves changes of their aggregation state inaddition to redox changes of regulatory cysteines.Herewe demonstrate that plants possess two different complexes containing the inactive forms (a) of NADP-GAPDH and PRK and (b) of only NADP-GAPDH, respectively, in darkened chloroplasts.
8p tumor12 22-04-2013 32 2 Download
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The activity of m-calpain, a heterodimeric, Ca 2+ -dependent cysteine protease appears to be modulated by membrane interactions involving oblique-orientated a-helix formation by a segment, GTAMRILGGVI, in the protein’s smaller subunit. Here, graphical and hydrophobic moment-based analyses predicted that this segment may form ana-helix with strong structural resemblance to the influenza virus peptide, HA2, a known oblique-orientateda-helix former.
9p tumor12 22-04-2013 34 5 Download
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Complement regulator C4b-binding protein (C4BP) and the anticoagulant vitamin K-dependent protein S form a high affinity complexin human plasma. C4BP is composed of sevena-chains and a uniqueb-chain, each chain comprising repeating complement control protein (CCP) modules. The binding site for protein S mainly involves the first of the threeb-chain CCPs (CCP1). However, recently it has been suggested that CCP2 of theb-chain also contributes to the binding of proteinS.
8p tumor12 20-04-2013 33 2 Download
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The Ca 2+ -induced transition in the troponin complex (Tn) regulates vertebrate striated muscle contraction. Tn was reconstituted with recombinant forms of troponin I (TnI) containing a single intrinsic 5-hydroxytryptophan (5HW). Fluorescence analysis of these mutants of TnI demonstrate that the regions in TnI that respond to Ca 2+ binding to the regulatoryN-domain of TnC are the inhibitoryregion (residues 96–116) and a neighboring region that includes position 121.
8p fptmusic 16-04-2013 39 4 Download
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Plant flavonoids are polyphenolic compounds, commonly found in vegeta-bles, fruits and many food sources that form a significant portion of our diet. These compounds have been shown to interact with several ATP-bind-ing cassette transporters that are linked with anticancer and antiviral drug resistance and, as such, may be beneficial in modulating drug resistance. This study investigates the interactions of six common polyphenols; querce-tin, silymarin, resveratrol, naringenin, daidzein and hesperetin with the multidrug-resistance-associated proteins, MRP1, MRP4 and MRP5. ...
16p fptmusic 12-04-2013 40 2 Download
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The activity of the digestiveb-glycosidase fromSpodoptera frugiperda (Sfbgly50, pH optimum 6.2) depends on E399 (pKa¼4.9; catalytic nucleophile) and E187 (pKa¼7.5; catalytic proton donor). Homology modelling of the Sfbgly50 active site confirms that R97 and Y331 form hydrogen bonds with E399. Site-directed mutagenesis showed that the substitution of R97 bymethionine or lysine increased the E399 pKa by 0.6 or 0.8 units, respectively, shifting the pH optima of these mutants to 6.5.
10p fptmusic 12-04-2013 35 3 Download
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Gas1p is a glycosylphosphatidylinositol-anchored plasma membrane glycoprotein ofSaccharomyces cerevisiaeand is a representative of Family GH72 of glycosidases/transgly-cosidases, which also includes proteins from human fungal pathogens. Gas1p, Phr1-2p from Candida albicansand Gel1p fromAspergillus fumigatushave been shown to be b-(1,3)-glucanosyltransferases required for proper cell wall assembly andmorphogenesis. Gas1p is organized into three modules: a catalytic domain; a cys-richdomain; andahighly O-glycosylated serine-rich region. ...
11p awards 05-04-2013 47 4 Download
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The eukaryotic translation initiation factor (eIF) 4E, is regulated by modulating both its phosphorylation and its availability to interact with the scaffold protein, eIF4G, to form the mature eIF4F complex. Here we show that treat-ment of C2C12 myoblasts with the proteasomal inhibitor, MG132 (N-carbobenzoxyl-Leu-Leu-leucinal), resulted in an early decrease inprotein synthesis rates followed by a partial recovery, reflecting the reprogramming of translation.
16p dell39 03-04-2013 45 4 Download
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We have investigated mutants of phytochrome Cph1 from the cyanobacter-ium SynechocystisPCC6803 in order to study chromophore–protein inter-actions. Cph1D2, the 514-residue N-terminal sensor module produced as a recombinant His6-tagged apoprotein in Escherichia coli, autoassembles in vitro to form a holoprotein photochemically indistinguishable from the full-length product.
15p inspiron33 26-03-2013 52 6 Download
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Palmitoylcarnitine, known to promote differentiation of neuroblastoma NB-2a cells as well as to inhibit protein kinase C (PKC) activity and to decrease phorbol ester binding, was shown previously to diminish the amount of complex formed between PKCdand its substrate GAP-43. In the present work we studied the effect of palmitoylcarnitine on the inter-action between PKCbII and its receptor RACK1.
12p inspiron33 26-03-2013 61 4 Download
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Tissue-type plasminogen activator (t-PA) has recently been identified as a modulator of neuronal plasticity and can initiate conversion of the pro-form of brain-derived neurotrophic factor (BDNF) into its mature form. BDNF also increases t-PA gene expression implicating t-PA as a downstream effector of BDNF function.
13p galaxyss3 19-03-2013 65 3 Download