The inhibition process

The purpose of the dissertation: Create low molecular weight, water-soluble chitosan with antifungal ability from chitosan by the degradation method by hydrogen peroxide agent to prevent effectly the anthracnose on post-harvest fruit and vegetables (mango, banana and chili pepper)

34p tunelove 11-06-2021 39 3   Download

Tomato is world’s one of the largest growing vegetable crop and ranks first among processing crops. It’s production suffers with many biotic and abiotic factors. Leaf blight disease caused by different species of Alternaria is one of the most dreadful diseases of tomato, causing huge economic losses. The present study was conducted in order to evaluate the efficacy of different fungicides against Alternaria alternata, one of cause for blight disease of tomato.

6p trinhthamhodang11 27-04-2021 28 3   Download

G-quadurplex (G4) formation plays a role in many biological processes such as replication, transcription, translation, and telomeric maintenance. Stabilization of G4 structure by peptide has recently emerged as a potential approach in the regulation of protein expression. In this study, we reported on regulation of cyan fluorescent protein (CFP) expression by the interaction of G4 and RNA helicase associated with AU-rich elements (RHAU) peptide in E. coli.

7p larachdumlanat127 02-01-2021 6 2   Download

Caffeine was isolated from dry green tea leaves and used as corrosion inhibitor. The aim of this paper is to study the corrosion inhibition behavior of caffeine with its different concentrations (from 0.01 g/L to 3.00 g/L) for CT3 steel in 1M HCl solution by the curve polarization measurements and surface examination studies. Experiment result showed that: as the concentration of caffeine increases, the inhibition efficiency increases; %IE max is approximately 83.27% at concentration of caffeine 3.00 g/L.

5p lamtan3547 04-11-2018 28 1   Download

The serpin plasminogen activator inhibitor type 1 (PAI-1) plays an important role in physiological processes such as thrombolysis and ®brinolysis, as well as pathophysiological processes such as thrombosis, tumor invasion and metas-tasis. In addition to inhibiting serine proteases, mainly tissue-type (tPA) and urokinase-type (uPA) plasminogen activators, PAI-1 interacts with di€erent components of the extracellular matrix, i.e. ®brin, heparin (Hep) and vitronectin (Vn).

9p research12 29-04-2013 25 3   Download

A number of antibiotics have been reported to disturb the decoding process in prokaryotic translation and to inhibit the function of various natural ribozymes. We investigated the e€ect of several antibiotics on in vitro splicing of a eukaryotic nuclear pre-mRNA (b-globin). Of the eight antibiotics studied, erythromycin, Cl-tetracycline and streptomycinwere identi®ed as splicing inhibitors in nuclear HeLa cell extract. TheKi values were 160, 180 and 230lM, respectively.

9p research12 29-04-2013 31 3   Download

important regulators of biological processes in animals and plants. MiRNAs regulate gene expression at the posttranscriptional level by binding to mRNAs and either inhibit translation or modify the stability of the mRNA. Due to the important biological role of miRNAs it is of great interest to study their expression level in the cells. Furthermore, miRNAs have been associated with cancer and other diseases [1] and miRNA expression can help in the diagnosis and prognostic of human disease [2,3].

11p zingzing09 24-04-2013 51 3   Download

ThemaltoseATP-binding cassette transporter ofSalmonella typhimurium is composed of a membrane-associated com-plex (MalFGK2) and a periplasmic receptor (MalE). In addition to its role in transport, the complex acts as a repressor ofmaltose-regulatedgene expressionand is subject to inhibition in the process of inducer exclusion. These activities are thought to be mediated by interactions of the ATPase subunit, MalK, with the transcriptional activator, MalT, and nonphosphorylated enzyme IIA of the glucose phosphotransferase system, respectively. ...

12p research12 23-04-2013 35 3   Download

Imidazolium trans-imidazoledimethyl sulfoxide-tetrachlo-roruthenate (NAMI-A) is a novel ruthenium-containing experimental antimetastatic agent. Compelling evidence ascribes apivotal role toendothelial cells in theorchestration of tumor angiogenesis and metastatic growth, suggesting antiangiogenic therapy as an attractive approach for anticancer treatment.

10p tumor12 22-04-2013 42 2   Download

Nitric oxide (NO • ) strongly inhibits the proliferation of human A431 tumour cells. It also inhibits tyrosine phos-phorylation of a 170-kDa band corresponding to the epidermal growth factor receptor (EGFR) and induces the phosphorylation at tyrosine residue(s) of a 58-kDa protein which we have denoted NOIPP-58 (nitric oxide-induced 58-kDa phosphoprotein). The NO • -induced phosphoryla-tion of NOIPP-58 is strictly dependent on the presence of EGF. Phosphorylation of NOIPP-58 and inhibition of the phosphorylation of the band corresponding to EGFR are both cGMP-independent processes. ...

10p fptmusic 16-04-2013 29 3   Download

Serpins are the largest family of protease inhibitors and are fundamental for the control of proteolysis in multicellular eukaryotes. Most eukaryote serpins inhibit serine or cysteine proteases, however, noninhibitory mem-bers have been identified that perform diverse functions in processes such as hormone delivery and tumour metastasis. More recently inhibitory ser-pins have been identified in prokaryotes and unicellular eukaryotes, never-theless, the precise molecular targets of these molecules remains to be identified....

6p fptmusic 12-04-2013 36 2   Download

We report here the first crystal structure of a stable isosteric analogue of 1,3-bisphospho-D-glyceric acid (1,3-BPGA) bound to the catalytic domain of Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase (gGAPDH)in which the two phosphoryl moieties interact with Arg249. This complex possibly illustrates a step of the catalytic process by which Arg249 may induce compression of the product formed, allowing its expulsion fromthe active site.

13p fptmusic 12-04-2013 70 3   Download

RNA helicase II⁄Guais a multifunctional nucleolar protein involved in ribosomal RNA processing inXenopus laevisoocytes and mammalian cells. Downregulation of Guausing small interfering RNA (siRNA) in HeLa cells resulted in 80% inhibition of both 18S and 28S rRNA production. The mechanisms underlying this effect remain unclear. Here we show that in mammalian cells, Guaphysically interacts with ribosomal protein L4 (RPL4), a component of 60S ribosome large subunit.

15p fptmusic 11-04-2013 36 2   Download

Fibrillization ofa-synuclein (a-Syn) is closely associated with the formation of Lewy bodies in neurons and dopamine (DA) is a potent inhibitor for the process, which is implicated in the causative pathogenesis of Parkin-son’s disease (PD). To elucidate any molecular mechanism that may have biological relevance, we tested the inhibitory abilities of DA and several analogs including chemically synthetic and natural polyphenols in vitro.

12p fptmusic 11-04-2013 43 2   Download

The urokinase-type plasminogen activator (uPA) receptor (uPAR) has been implicated in signal transduction and biological processes including cancer metastasis, angiogenesis, cell migration, and wound healing. It is a specific cell surface receptor for its ligand uPA, which catalyzes the formation of plasmin from plasminogen, thereby activating the proteolytic cascade that contributes to the breakdown of extracellular matrix, a key step in cancer metastasis.

11p fptmusic 11-04-2013 46 3   Download

14-3-3 Proteins are dimeric phophoserine-binding molecules that participate in important cellular processes such as cell proliferation, cell-cycle control and the stress response. In this work, we report that several isoforms of 14-3-3s are expressed in neonatal rat cardiomyocytes. To understand their function, we utilized a general 14-3-3 peptide inhibitor, R18, to disrupt 14-3-3 functions in cardiomyocytes.

0p awards 06-04-2013 38 1   Download

The phosphorylation-dephosphorylation of serine and threonine residues of calponin is known tomodulatein vitro its interactionwithF-actin and is thought to regulate several biological processes in cells, involving either of the calponin isoforms. Here, we identify, for the first time, tyrosine-phosphorylated calponin h3 within COS 7 cells, before and after their transfection with the pSV vector containing cDNA encoding the cytoplasmic, Src-related, tyrosine kin-ase, Fyn.

9p dell39 03-04-2013 41 4   Download

A protocol to follow the processing of angiotensin I into angiotensin II by rabbit angiotensin-converting enzyme (ACE) and its inhibition by a novel natural antagonist, the leech osmoregulator factor (LORF) using capillary zonal electrophoresis is described. The experiment was carried out using the Beckman PACE system and steps were taken to determine (a) the migration profiles of angiotensin and its yielded peptides, (b) the minimal amount of angiotensin II detected, (c) the use of different electrolytes and (d) the concentration of inhibitor. ...

6p dell39 03-04-2013 44 4   Download

Alzheimer’s disease and Creutzfeldt–Jakob disease are the best-known examples of a group of diseases known as the amyloidoses. They are char-acterized by the extracellular deposition of toxic, insoluble amyloid fibrils. Knowledge of the structure of these fibrils is essential for understanding the process of pathology of the amyloidoses and for the rational design of drugs to inhibit or reverse amyloid formation.

12p dell39 27-03-2013 33 4   Download

The formation of amyloid fibrils is associated with various human medical disorders of unrelated origin. Recent research indicates that self-assembled amyloid fibrils are also involved in physiological processes in several micro-organisms. Yet, the molecular basis for the recognition and self-assembly processes mediating the formation of such structures from their soluble protein precursors is not fully understood.

8p dell39 27-03-2013 38 5   Download