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Báo cáo khoa học: Crystal structure of the BcZBP, a zinc-binding protein from Bacillus cereus

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:11

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Recurrent missense fibroblast growth factor receptor 3 (FGFR3) mutations have been ascribed to skeletal dysplasias of variable severity including the lethal neonatal thanatophoric dysplasia types I (TDI) and II (TDII). To elucidate the role of activating mutations causing TDI on receptor traffick-ing and endocytosis, a series of four mutants located in different domains of the receptor were generated and transiently expressed.

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Nội dung Text: Báo cáo khoa học: Crystal structure of the BcZBP, a zinc-binding protein from Bacillus cereus

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