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Báo cáo khoa học: Direct interaction between CD91 and C1q

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:12

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C1q-mediated removal of immune complexes and apoptotic cells plays an important role in tissue homeostasis and the prevention of autoimmune conditions. It has been suggested that C1q mediates phagocytosis of apop-totic cells through a receptor complex assembled from CD91 (a-2- macro-globulin receptor, or low-density lipoprotein receptor-related protein) and calreticulin, with CD91 being the transmembrane part and calreticulin act-ing as the C1q-binding molecule.

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