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Báo cáo khoa học: Early signaling events induced by 280-nm UV irradiation

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:7

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The depletion of stratospheric ozone results in increasedUV (ultraviolet) light below 300 nm, and has signi®cant e€ects onbiological systems.Tobetterunderstand the e€ectsofUV in this range, early signaling events induced by monochro-maticUV lightwere investigatedusing the chickenBcell line DT40 andmutants lacking protein tyrosine kinases (PTKs). AmongMAPkinase familyproteins, P38MAPkinase (P38) was selectively and immediately activated by 280 nm UV light in cultured DT40 cells.

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