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Báo cáo khoa học: Functional characterization of front-end desaturases from trypanosomatids depicts the first polyunsaturated fatty acid biosynthetic pathway from a parasitic protozoan
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A survey of the three kinetoplastid genome projects revealed the presence of three putative front-end desaturase genes inLeishmania major, one in Trypanosoma bruceiand two highly identical ones (98%) inT. cruzi. The encoded gene products were tentatively annotated as D8, D5 and D6 desaturases for L. major, and D6 desaturase for both trypanosomes.
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