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Báo cáo khoa học: Inhibition of Hsp90 function delays and impairs recovery from heat shock

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:13

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The induction of the heat shock response as well as its termination is auto-regulated by heat shock protein activities. In this study we have investi-gated whether Hsp90 functional protein levels influence the characteristics and duration of the heat shock response. Treatment of cells with several benzoquinone ansamycin inhibitors of Hsp90 (geldanamycin, herbimycin A) activated a heat shock response in the absence of heat shock, as reported previously.

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Nội dung Text: Báo cáo khoa học: Inhibition of Hsp90 function delays and impairs recovery from heat shock

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