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Báo cáo khoa học: Mechanism of protection of peroxidase activity by oscillatory dynamics

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:9

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The peroxidase–oxidase reaction is known to involve react-ive oxygen species as intermediates. These intermediates inactivatemany types of biomolecules, including peroxidase itself. Previously,wehave shown that oscillatorydynamics in the peroxidase–oxidase reaction seem to protect the enzyme frominactivation. It was suggested that this is due to a lower average concentration of reactive oxygen species in the oscillatory state compared to the steady state. Here, we studied the peroxidase–oxidase reaction with either 4-hydroxybenzoic acid or melatonin as cofactors. ...

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