intTypePromotion=1
zunia.vn Tuyển sinh 2024 dành cho Gen-Z zunia.vn zunia.vn
ADSENSE

Báo cáo khóa học: Membrane interaction and cellular internalization of penetratin peptides

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:11

45
lượt xem
3
download
 
  Download Vui lòng tải xuống để xem tài liệu đầy đủ

Penetratin is a 16-residue peptide [RQIKIWFQNRRM KWKK(43–58)]derived from the Antennapedia homeo-domain, which is used as a vector for cellular internalization of hydrophilic molecules. In order to unravel themembrane translocation mechanism, we synthesized new penetratin variants. The contribution of the positively charged residues was studied by double substitutions of Lys and/or Arg resi-dues to Ala, while the specific contribution of Trp48 and Trp56 was studied by individual substitution of these resi-dues to Phe. ...

Chủ đề:
Lưu

Nội dung Text: Báo cáo khóa học: Membrane interaction and cellular internalization of penetratin peptides

ADSENSE

CÓ THỂ BẠN MUỐN DOWNLOAD

 

Đồng bộ tài khoản
3=>0