Báo cáo khoa học: Oxidase activity of a flavin-dependent thymidylate synthase
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Flavin-dependent thymidylate synthases (FDTS) catalyze the production of dTMP from dUMP and N 5 ,N 10 -methylene-5,6,7,8-tetrahydrofolate (CH2H4 folate). In contrast to human and other classical thymidylate synth-ases, the activity of FDTS depends on a FAD coenzyme, and its catalytic mechanism is very different.
Chủ đề:
- Scientific reports
- scientific research
- biochemistry
- Flavin-dependent thymidylate synthases (FDTS) catalyze the production of dTMP from dUMP and N 5
- N 10 -methylene-5
- 6
- 7
- 8-tetrahydrofolate (CH2H4 folate). In contrast to human and other classical thymidylate synth-ases
- the activity of FDTS depends on a FAD coenzyme
- and its catalytic mechanism is very different.
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