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Báo cáo khoa học: Phosphorylation-dependent binding of human transcription factor MOK2 to lamin A⁄C
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Human MOK2 is a DNA-binding transcriptional repressor. Previously, we identified nuclear lamin A⁄C proteins as protein partners of hsMOK2. Fur-thermore, we found that a fraction of hsMOK2 protein was associated with the nuclear matrix. We therefore suggested that hsMOK2 interactions with lamin A⁄C and the nuclear matrix may be important for its ability to repress transcription.
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