intTypePromotion=1
zunia.vn Tuyển sinh 2024 dành cho Gen-Z zunia.vn zunia.vn
ADSENSE

Báo cáo khoa học: Proteolytic activation of internalized cholera toxin within hepatic endosomes by cathepsin D

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:13

35
lượt xem
3
download
 
  Download Vui lòng tải xuống để xem tài liệu đầy đủ

We have defined thein vivo andin vitro metabolic fate of internalized chol-era toxin (CT) in the endosomal apparatus of rat liver. In vivo, CT was internalized and accumulated in endosomes where it underwent degrada-tion in a pH-dependent manner. In vitro proteolysis of CT using an endo-somal lysate required an acidic pH and was sensitive to pepstatin A, an inhibitor of aspartic acid proteases.

Chủ đề:
Lưu

Nội dung Text: Báo cáo khoa học: Proteolytic activation of internalized cholera toxin within hepatic endosomes by cathepsin D

ADSENSE

CÓ THỂ BẠN MUỐN DOWNLOAD

 

Đồng bộ tài khoản
7=>1