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Báo cáo khoa học: The soluble form of the membrane-bound transferrin homologue, melanotransferrin, inefficiently donates iron to cells via nonspecific internalization and degradation of the protein

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:11

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Melanotransferrin (MTf) is a membrane-bound transferrin (Tf) homologue foundparticularly inmelanoma cells. Apart frommembrane-boundMTf, a soluble formof themolecule (sMTf) has been identified in vitro [Food, M.R., Rothen-berger, S., Gabathuler, R., Haidl, I.D., Reid, G. & Jefferies, W.A. (1994)J. Biol. Chem.269, 3034–3040] and in vivo in Alzheimer’s disease. However, nothing is known about the functionof sMTf or its role inFeuptake.

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Nội dung Text: Báo cáo khoa học: The soluble form of the membrane-bound transferrin homologue, melanotransferrin, inefficiently donates iron to cells via nonspecific internalization and degradation of the protein

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