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Báo cáo Y học: Mammalian HSP60 is quickly sorted into the mitochondria under conditions of dehydration

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:8

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There are few reports concerning the sortingmechanisms of mammalian HSP60 into the mitochondria from the cyto-plasm. In the present study we investigated the protein import system. Based on immunoblotting and immuno-histochemistry, HSP60 was detected in both the cytoplasm andmitochondria. The purified cytoplasmicHSP60 showed chaperone activity, and the protein was imported into the mitochondriain vitro by a mitochondrial import assay.

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Nội dung Text: Báo cáo Y học: Mammalian HSP60 is quickly sorted into the mitochondria under conditions of dehydration

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