Báo cáo Y học: Mammalian HSP60 is quickly sorted into the mitochondria under conditions of dehydration
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There are few reports concerning the sortingmechanisms of mammalian HSP60 into the mitochondria from the cyto-plasm. In the present study we investigated the protein import system. Based on immunoblotting and immuno-histochemistry, HSP60 was detected in both the cytoplasm andmitochondria. The purified cytoplasmicHSP60 showed chaperone activity, and the protein was imported into the mitochondriain vitro by a mitochondrial import assay.
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