Functional specification

Prostate cancer (PC) with bone metastasis has many clinical symptoms that very much affected to the patient’s quality of life (QoL). Improving cancer patient’s QoL is a mission for the health care professional workers. The study using questionaires SF-36 and UCLA-PCI-SF- a simple and common methods to evaluate the progress of orchiectomy treatment for bone metastases PC to assess the QoL and prostate-specific functions before and after orchiectomy.

7p viyamanaka 06-02-2025 1 1   Download

This study examines the pivotal role of Supreme Audit Institutions (SAIs) in monitoring the implementation of Sustainable Development Goals (SDGs) by governments. Qualitative research method was used by synthesizing and analyzing important sources of documents from organizations such as Worldbank, United Nation; Intosai and the website of the National Supreme Audit Institution to explore the specific functions of the Supreme Audit Institution towards the goal of sustainable development.

5p viyamanaka 06-02-2025 1 1   Download

The authors develop a system of differential equations describing the motion of the structural system equipped with DFP bearings. The Runge-Kutta numerical method, specifically the ode15s function in MATLAB, was used to solve these equations. The results of the calculations provide a comparison of the damping efficiency of the structural system with and without the use of DFP bearings, assessing the effectiveness of vibration isolation during an earthquake, with three components X, Y, and vertical considered.

5p vibenya 31-12-2024 9 2   Download

Toyota tundra – new features is a 4.6-liter, 32-valve DOHC V8.This engine uses the Dual Variable Valve Timing-intelligent (Dual VVT-i) system, Direct Ignition System (DIS), Acoustic Control Induction System (ACIS), Electronic Throttle Control System-intelligent (ETCS-i), air injection system and Exhaust Gas Recirculation (EGR) control. These control functions achieve improved engine performance, fuel economy, and clean emissions.

95p endlesslovelp 09-03-2015 73 10   Download

This thesis intends to develop application-level access control models to address several major security issues in enterprise environments. The first goal is to provide simple and efficient authorization specifications to reduce the complexity of security management. The second goal is to provide dynamic access control for Web service applications. The third goal is to provide an access control framework for Semantic Web services. In this thesis, an Authorization-Function-Based Role-based Access Control (FB-RBAC) model is proposed for controlling enterprise systems at the application level.

182p runthenight07 01-03-2023 14 3   Download

The specific research objectives of this study are: 1. The development of a high throughput method for evaluation of alloys (5xxx Al as model materials in this work) subject to pitting; 2. Understanding the roles of variation in functional groups' in determining the inhibition efficiency; 3. Elucidating the inhibition mechanisms; and 4. Unveiling the role of intermetallic present in Al matrix and their contribution to the inhibition mechanism, particularly the long-term durability of the inhibitor systems.

104p runthenight04 02-02-2023 13 2   Download

The broad aim of this research project is to optimize planned and emergency maintenance tasks and timings for tram tracks. Consistent with that broad aim, the following specific objectives are identified: Understand the factors affecting the degradation of tram tracks; develop a degradation prediction model for tracks as a function of the influencing factors; evaluate the time and type of maintenance required for deteriorated rail tracks.

101p runthenight04 02-02-2023 9 2   Download

The main objective of this research study is to empirically test if a traditional brand equity model is applicable to online companies and to ascertain its nomological validity.

240p runthenight04 02-02-2023 11 3   Download

uận văn sẽ đề xuất một ngôn ngữ mô hình hóa chuyên biệt miền có tên là Functional Requirement Specification Language (FRSL) để đặc tả ca sử dụng. Hướng tiếp cận này bao gồm quá trình xác định các khái niệm của miền đặc tả ca sử dụng, từ đó xây dựng cú pháp trừu tượng cho ngôn ngữ dưới dạng metamodel.

46p tamynhan0 04-07-2020 42 4   Download

Regulator of G-protein signaling (RGS) proteins were originally identified as negative regulators of G-protein-coupled receptor (GPCR) signaling via their GTPase-accelerating protein (GAP) activity. All RGS proteins contain evolutionarily conserved RGS domain; however, they differ in their size and regulatory domains. RGS1 and RGS10 are smaller than other RGS proteins, and their functions involve various inflammatory responses including autoimmune responses in both the periphery and the central nervous system (CNS). Neuroinflammation is the chronic inflammatory response in the CNS.

5p caothientrangnguyen 09-05-2020 30 2   Download

Regulator of G protein signaling (RGS) proteins are gatekeepers regulating the cellular responses induced by G protein-coupled receptor (GPCR)-mediated activation of heterotrimeric G proteins. Specifically, RGS proteins determine the magnitude and duration of GPCR signaling by acting as a GTPase-activating protein for Gα subunits, an activity facilitated by their semiconserved RGS domain. The R7 subfamily of RGS proteins is distinguished by two unique domains, DEP/DHEX and GGL, which mediate membrane targeting and stability of these proteins.

13p caothientrangnguyen 09-05-2020 30 1   Download

Bài giảng "Công nghệ phần mềm - Chapter 3: Requirements Engineering" presentation of content: Functional and non-functional requirements, the software requirements document, requirements specification, requirements engineering processes,... Invite you to reference.

11p doinhugiobay_15 25-02-2016 85 4   Download

In recent years, legislative and market requirements have driven the need to reduce fuel consumption while meeting increasingly stringent exhaust emissions. This trend has dictated increasing complexity in automotive engines and new approaches to engine design. A key research objective for the automotive engineering community has been the potential combination of gasoline-engine specific power with diesel-like engine efficiency in a cost-competitive, production-feasible power train.

21p minhtrong90 06-05-2013 91 6   Download

Stress-activated protein kinase (SAPK) signaling plays essential roles in eliciting adequate cellular responses to stresses and proinflammatory cytokines. SAPK pathways are composed of three successive protein kinase reactions. The phosphorylation of SAPK signaling components on Ser/Thr or Thr/Tyr residues suggests the involvement of various protein phosphatases in the negative regulation of these systems.

7p research12 01-06-2013 54 4   Download

Thyrotropin-releasing hormone receptor (TRHR) has already been cloned in mammals where thyrotropin-releas-inghormone (TRH) isknowntoactasapowerful stimulator of thyroid-stimulating hormone (TSH) secretion. The TRH receptor of amphibians has not yet been characterized, although TRH is specifically important in the adaptation of skin color to environmental changes via the secretion of a-melanocyte-stimulating hormone (a-MSH).

11p research12 23-04-2013 33 4   Download

Short-chaindehydrogenases/reductases (SDRs) are enzymes of great functional diversity. Even at sequence identities of typically only 15–30%, specific sequence motifs are detect-able, reflecting common folding patterns. We have devel-oped a functional assignment scheme based on these motifs and we find five families. Two of these families were known previously and are called
classical and
extended families, but they are now distinguished at a further level based on coenzyme specificities.

9p research12 23-04-2013 39 3   Download

An RBCC (RING finger, B-box, and coiled-coil) protein was identified that belongs to the superfamilyof zinc-binding proteins and is specifically expressed in the gill of eel, Anguilla japonica. Euryhaline fishes such as eels canmigrate between freshwater and seawater, which is considered to be accomplished by efficient remodeling of the architecture and function of the gill, a major osmoregulatory organ.

10p tumor12 22-04-2013 36 3   Download

Understanding peroxidase function in plants is complicated by the lackof substrate specificity, the highnumber of genes, their diversity in structure and our limited knowledge of peroxidase gene transcription and translation. In the present study we sequenced expressed sequence tags (ESTs) enco-ding novel heme-containing class III peroxidases from Arabidopsis thalianaand annotated 73 full-length genes identified in the genome.

19p tumor12 22-04-2013 31 2   Download

Tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) has been known to induce tumor-specific apoptosis and to share the structural and functional char-acteristics with the proteins of TNF family. Recently, the crystal structure of humanTRAIL showed that TRAIL is a homotrimeric protein whose subunits contain mainly b-sheets. We characterized the structural changes of recombinant human TRAIL induced byacidification and the biological implication of the structural characteristics at acidic pH in the interaction with the lipid bilayer. ...

8p tumor12 22-04-2013 50 2   Download

14-3-3 proteins play an important role in a multitude of signalling pathways. The interactions between 14-3-3 and other signalling proteins, such as Raf and KSR (kinase suppressor of Ras), occur in a phospho-specific manner. Recently, a phosphorylation-independent interaction has been reported to occur between 14-3-3 and several proteins, for example 5-phosphatase, p75NTR-associated cell death executor (NADE) and the bacterial toxin Exoenzyme S (ExoS), an ADP-ribosyltransferase from Pseudomonas aeruginosa. ...

9p tumor12 22-04-2013 29 3   Download