Levels and complexity

This thesis intends to develop application-level access control models to address several major security issues in enterprise environments. The first goal is to provide simple and efficient authorization specifications to reduce the complexity of security management. The second goal is to provide dynamic access control for Web service applications. The third goal is to provide an access control framework for Semantic Web services. In this thesis, an Authorization-Function-Based Role-based Access Control (FB-RBAC) model is proposed for controlling enterprise systems at the application level.

182p runthenight07 01-03-2023 12 3   Download

Cycads occur in lowland forests and are threatened by their degradation, fragmentation and over-exploitation. Our results indicate that cycad population sizes were very small (less 100 individuals) with high propagules. These increased mating between closely related individuals growing in clumps. The allozyme data show although all studied cycads maintained high levels of genetic diversity, an average of 0.556 (0.491 in C. hoabinhensis to 0.598 in C. chevalieri ), the degree of inbreeding was high.

10p 12120609 01-06-2020 17 3   Download

With Europe’s ageing fleet of nuclear reactors operating closer to their safety limits, the monitoring of such reactors through complex models has become of great interest to maintain a high level of availability and safety.

9p christabelhuynh 29-05-2020 10 1   Download

This is a research topic with a wide, complex content. Within the scope of this thesis, the author focuses on the quality of examination and processing of legal documents by Provincial People’s council and People’s committeel in Vietnam, accordingly, concentrates on examining and processing the legal documents issued by Provincial People’s council and People’s committeel without extension of examination of the inspection activities of the Provincial People’s council and People’s committeel to the documents of the lower level within the province.

26p bibianh 25-09-2019 46 4   Download

A diagnostic tool for assessing organisational readiness for complex change outlines the development of a new diagnostic tool that combines macro and micro levels of analysis in order to enable organisations to gauge their preparedness for complex change.

18p tungkhtn 17-07-2016 40 3   Download

Zinc (Zn), an endogenous regulator of apoptosis, and has abilitiesboth to induceapoptosis and inhibit the inductionof apoptosis via the modulation of caspase activity. Due to the multifunctions of Zn, the intracellular Zn level is strictly regulated by a complex system in physiological and patho-logical conditions. The commitment of Zn to the regulation of apoptosis is not fully understood. In the present study, we investigated the role of intracellular Zn level in the induction of apoptosis in human leukemia cells (HL-60 cells) using a Zn ionophore [pyrithione (Py)]....

8p tumor12 22-04-2013 28 2   Download

In Saccharomyces cerevisiae, which uses the nonlinear pathway of arginine biosynthesis, the first two enzymes, N-acetylglutamate synthase (NAGS) andN-acetylglutamate kinase (NAGK), are controlled by feedback inhibition. We have previously shown that NAGS andNAGKassociate in a complex, essential to synthase activity and protein level [Abadjieva,A., Pauwels,K.,Hilven, P.&Crabeel,M. (2001) J.Biol.Chem.276, 42869–42880].

11p tumor12 20-04-2013 43 4   Download

The pyruvate dehydrogenase complex (PDC) is subjected to multiple interacting levels of control in plant cells. The first level is subcellular compartmentation. Plant cells are unique inhaving twodistinct, spatially separated forms of the PDC; mitochondrial (mtPDC) and plastidial (plPDC). The mtPDCis the site of carbon entry into the tricarboxylic acid cycle, while the plPDCprovides acetyl-CoAandNADHfor de novofatty acid biosynthesis.

7p tumor12 20-04-2013 30 2   Download

An efficient bacterial expression system of cyanobacterium Synechocystissp. PCC 6803 heme oxygenase gene, ho-1, has been constructed, using a synthetic gene. A soluble protein was expressedat high levels and was highly purified, for the first time. The protein binds equimolar free hemin to catabolize the boundhemin to ferric-bili-verdin IXa in the presence of oxygen andreducing equivalents, showing the heme oxygenase activity. During the reaction, verdoheme intermediate is formed with the evolution of carbon monoxide. ...

12p tumor12 20-04-2013 32 4   Download

Functional diversity of potassium channels in both prokaryotic and euk-aryotic cells suggests multiple levels of regulation. Posttranslational regula-tion includes differential subunit assembly of homologous pore-forming subunits. In addition, a variety of modulatory subunits may interact with the pore complex either statically or dynamically. Kv2.1 is a delayed recti-fier potassium channel isolated by expression cloning.

13p fptmusic 11-04-2013 36 2   Download

During adipocyte differentiation, there is an underlying complex series of gene expressions. We have previously isolated many genes whose expres-sion levels are quickly elevated by the addition of inducers to mouse 3T3-L1 preadipocyte cells. Here we report the isolation and characterization of SLC39A14, a member of the LZT proteins, one of the subfamilies of ZIP transporters.

0p awards 06-04-2013 36 2   Download

The Tat system transports folded proteins across the bacterial cytoplasmic membrane and the thylakoid membrane of plant chloroplasts. Substrates are targeted to the Tat pathway by signal peptides containing a pair of consecutive arginine residues. The membrane proteins TatA, TatB and TatC are the essential components of this pathway inEscherichia coli.

13p inspiron33 23-03-2013 40 3   Download

Plasma concentrations of free fatty acids are increased in metabolic syn-drome, and the increased fatty acids may cause cellular damage via the induction of oxidative stress. The present study was designed to determine whether the increase in fatty acids can modify the free sulfhydryl group in position 34 of albumin (Cys34) and enhance the redox-cycling activity of the copper–albumin complex in high-fat diet-induced obese mice.

9p galaxyss3 21-03-2013 40 3   Download

Iron regulatory protein-1 binding to the iron-responsive element of mRNA is sensitive to iron, oxidative stress, NO, and hypoxia. Each of these agents changes the level of intracellular ATP, suggesting a link between iron levels and cellular energy metabolism.

12p galaxyss3 19-03-2013 32 3   Download

Tissue factor pathway inhibitor (TFPI) is a multivalent Kunitz-type prote-ase inhibitor that primarily inhibits the extrinsic pathway of blood coagula-tion. It is synthesized by various cells and its expression level increases in inflammatory environments.

10p galaxyss3 19-03-2013 23 3   Download

The innate immune system has provided an excellent model for study-ing complex regulatory networks at the levels of signal transduction and transcription. Virus infection of mammalian cells triggers the coor-dinate activation of multiple signaling pathways leading to the activa-tion of specific sets of transcription factors that assemble on the interferon-b (IFN-b) gene enhancer to form an enhanceosome.

61p galaxyss3 07-03-2013 42 5   Download

Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily that modulate target gene expression in response to fatty acid ligands. Their regulation by post-translational modifications has been reported but is poorly understood.

9p media19 04-03-2013 43 1   Download

Receptors should be properly analysed in view of the microenvironment in which they are embedded. Therefore, the concept of ‘receptosome’ was for-mulated to the complex interactions taking place between receptors and other proteins at the plasma membrane level, and to explain very heteroge-neous or divergent cellular responses to common epigenetic factors and modifications to the extracellular environment.

12p vinaphone15 27-02-2013 42 2   Download

Sexual differentiation inSchizosaccharomyces pombeis triggered by nutri-ent starvation and is downregulated by cAMP. Screening programs have identified the moc1/sds23, moc2/ded1, moc3andmoc4/zfs1genes as inducers of sexual differentiation, even in the presence of elevated levels of cAMP.

18p vinaphone15 25-02-2013 16 2   Download

Pathophysiologic responses in brain after stroke are highly complex. Thus far, a singular focus on saving neurons alone has not revealed any clinically effective neuroprotectants. To address this limitation, the concept of a neu-rovascular unit was developed. Within this conceptual framework, brain function and dysfunction are manifested at the level of cell–cell signaling between neuronal, glial and vascular elements.

9p vinaphone15 25-02-2013 35 2   Download