Significant function

Data was analyzed based on color-coded themes, which results in four significant findings: (1), the diversity of children’s oral language functions; (2), the Participant and Spectator roles of language in connection to embedded speech and displaced speech; (3), the interaction of Girl Talk and Boy Talk; and (4), the children’s peer support through Zone of Proximal Development.

11p viling 11-10-2024 1 0   Download

This study employs the tight-binding density functional method GFN1-xTB to investigate the structural and electronic properties of TiO2-ZnO and TiO2-ZnO composite materials modified by Li, Na, K, and Fe metals. Computational analyses reveal the formation of weak covalent bonds between the TiO2 and ZnO components within the composite system. Doping TiO2-ZnO with metals induces significant alterations in the electronic structure, particularly in terms of ionization energy and global electrophilic index.

5p vikwong 29-09-2024 2 1   Download

This thesis focuses on the skills and attributes required by Chief Executive Officers (CEOs) and senior staff as leaders and managers in the residential aged care services (RACS) sector. It makes a significant contribution to this field of inquiry by utilising original research to examine the capabilities needed to meet the challenges faced within this industry sector.

407p runthenight04 02-02-2023 2 2   Download

This review describes how UFL will expand the scope of applications and significantly improve the ontological value of natural leather. Significantly, UFL is expected to boost the sustainable development of conventional leather industry and the next-generation of advanced functional bio-based materials.

14p meyerowitz 25-12-2021 9 0   Download

The aim of our in vitro study was to assess the potential effect of BPF on H295R cells mitochondrial activity, metabolic activity, membrane integrity, lysosomal function, and testosterone synthesis. Adrenocortical carcinoma cells were cultivated during 24 h in the presence of BPF (0.1, 0.5, 1, 10, 25, 50, 75, 100, 300, 500 μM). Exposure doses of BPF caused a significant decrease of mitochondrial activity starting from 1 μM, we observed a slight increase in mitochondrial activity at the lowest concentration (0.1 μM).

4p mudbound 10-12-2021 13 1   Download

In this paper, we underline the significant role of intermediaries in boosting absorptive capacity in small and medium-sized enterprises by introducing a framework that expresses intermediaries' functions and their services in absorptive capacity as an essential element of successful knowledge and technology transfer.

10p larachdumlanat129 14-01-2021 14 2   Download

The formulae for the decay width and numerical results are obtained. We have calculated the conclusion of the one-loop vertex correction, wave-function correction and renormalization of the bare couplings to the decay width. We revealed that the effect of the complex parameters At and Ab could be quite significant in a large region of the MSSM parameter space.

6p tamynhan8 04-11-2020 16 4   Download

India has witnessed significant growth in the manufacture of automobiles. Growth in vehicle population results in several environmental issues. Regulators have been controlling the emissions by setting standards.

6p lucastanguyen 01-06-2020 30 3   Download

To assess the clinical significance of electrophysiological, functional, and morphometric studies of the optic nerve in patients with serous meningitis during the recovery period.

8p lucastanguyen 01-06-2020 15 2   Download

The aim of this research is to discover how senior managers view the impacts of the recession on training and development in Ireland and to identify problems they have had to face and how they have managed through the recession and beyond. The research has found that training is regarded as hugely important despite of or in fact of the recession and managers are willing to do what they can to ensure they can keep this function operating. This has led to some innovative and extremely effective training methods.

131p nguyenyenyn117 18-06-2019 64 7   Download

The reslult suggest that frequency and consistency of defecation, as well as clinical symptoms were improved significantly when using lactulose with 2 ml/ kg/day. The mean weekly stool frequency improved from 1.9 ± 0.8 times to 4.9 ± 1.8 times after 1 month and to 5.9 ± 1.4 times after 3 months of treatment (p < 0.01).

7p cumeo4000 01-08-2018 15 1   Download

After studying this chapter, you will be able to: Define leadership and leadership effectiveness Explain why people need leadership Discuss the major obstacles to effective leadership Compare and contrast leadership and management List the roles and functions of leaders and managers Summarize the debate over the role and impact of leadership in organizations.

40p sony_12 25-06-2013 71 8   Download

CYP73 enzymes are highly conserved cytochromes P450 in plant species that catalyse the regiospecific 4-hydroxylation ofcinnamicacid to formprecursorsofligninandmanyother phenolic compounds. A CYP73A1 homology model based on P450 experimentally solved structures was used to iden-tify active site residues likely togovern substrate binding and regio-specific catalysis. The functional significance of these residues was assessed using site-directedmutagenesis.

12p tumor12 20-04-2013 40 3   Download

The gene encodingBacillus subtilisUMP kinase (pyrH/ smbA) is transcribed in vivo into a functional enzyme, which represents approximately 0.1% of total soluble proteins. The specific activity of the purified enzyme under optimal conditions is 25 unitsÆmg )1 of protein. In the absenceofGTP,theactivityofB. subtilisenzyme is less than 10% of its maximum activity. Only dGTP and 3¢-anthraniloyl-2¢-deoxyguanosine-5¢-triphosphate (Ant-dGTP) can increase catalysis significantly.

9p tumor12 20-04-2013 33 2   Download

Cryptochromes are blue-light photoreceptors sharing sequence similarity to photolyases, a class of flavoenzymes catalyzing repair ofUV-damagedDNAvia electron transfer mechanisms. Despite significant amino acid sequence simi-larity in both catalytic and cofactor-binding domains, cryptochromes lack DNA repair functions associated with photolyases, and the molecular mechanism involved in cryptochrome signaling remains obscure.

8p tumor12 20-04-2013 38 3   Download

The crystal structure of theSchizosaccharomyces pombe Holliday junction resolvase Ydc2 revealed significant struc-tural homology with the Escherichia coliresolvase RuvC but Ydc2 contains a small triple helical bundle that has no equivalent in RuvC.Two of thea-helices that form this bundle show homology to a putative DNA-binding motif known as SAP.To investigate the biochemical function of the triple-helix domain, truncated Ydc2 mutants were expressed inE.coliand in fission yeast.

11p fptmusic 16-04-2013 35 4   Download

In rodents, the olfactory epithelium(OE) canbe divided into four topographically distinct zones, and eachmember of the odorant receptor(OR) gene family is expressed only in one particular zone. To study the functional significance of the zonal structure of the OE, we searched for genes expressed in a zone-specific manner by using the differential display method. Among the clones isolated from the rat OE, we characterized a novel olfactory protein termed O-MACS, a member of the medium-chain acyl-CoA synthetase family....

10p fptmusic 16-04-2013 39 3   Download

Folate is an essential vitamin involved in a number of biological processes. High affinity folate binding proteins (FBPs) exist both as glycosylphospha-tidylinositol-linked, membrane associated folate binding proteins and as soluble FBPs in plasma and some secretory fluids such as milk, saliva and semen. The function and significance of FBPs are unresolved, however, it has been suggested that they may facilitate folate uptake, e.g. during suck-ling.

8p fptmusic 11-04-2013 40 2   Download

Analysis of a draft nuclear genome sequence of the diatomThalassiosira pseudonana revealed the presence of 11 open reading frames showing significant similarity to functionally characterized fatty acid front-end desaturases. The corresponding genes occupy discrete chromosomal loca-tions as determined by comparison with the recently published genome sequence. Phylogenetic analysis showed that two of the T. pseudonana desaturase (Tpdes) sequences grouped with proteobacterial desaturases that lack a fused cytochrome b5 domain. ...

12p fptmusic 11-04-2013 32 2   Download

Whereas most membrane receptors are oligomeric entities, G-protein-coupled receptors have long been thought to function as monomers. Within the last 15 years, accumulating data have indicated that G-protein-coupled receptors can form dimers or even higher ordered oligomers, but the gen-eral functional significance of this phenomena is not yet clear.

9p fptmusic 11-04-2013 37 3   Download