Báo cáo khoa học: Functional interaction of diphenols with polyphenol oxidase
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Polyphenol oxidase (PPO) catalyzes the oxidation ofo-diphenols to their respective quinones. The quinones autopolymerize to form dark pigments, an undesired effect. PPO is therefore the target for the development of antibrowning and antimelanization agents. A series of phenolic compounds experimentally evaluated for their binding affinity and inhibition constants were computationally docked to the active site of catechol oxidase.
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