Hepatitis B virus

Hepatitis B infection remains a global health problem, with progression to acute-chronic hepatitis, severe liver failure, and death making hepatitis B one of the most serious infections worldwide. The disease is most widely transmitted from an infected mother to her baby, after exposure to infected blood or body fluids or unsafe sexual contact.

6p viharuno 03-01-2025 2 2   Download

Hepatitis A là một trong 5 loại virus truyền nhiểm gây ra bệnh viêm gan cho người, đó là Hepatitis A, B, C, D và E. Loại virus này hiếm thấy ở những nước có hệ thống vệ sinh công cộng tốt như ở Mỹ. Tuy vậy hàng năm ước tính có khoảng 100 người chết do viêm gan có liên quan đến virus Hepatitis A (theo tài liệu CDC1) trong số 30 – 50.000 ca bệnh, hao tốn trên 300 triệu USD

80p lalan38 29-03-2013 122 19   Download

The current research project genotyped HAV RNA by using protocols and primer sets designed by HAVNET. It collected and genotyped previous HAV-positive samples in VIDRL sample bank, and the results were used to establish epidemiological and molecular database of the HAV strains. The database was used to investigate the relationship between the current diagnostic samples and the previous HAV infection cases. It was expected to identify the source of the hepatitis A infection.

158p runthenight04 02-02-2023 8 3   Download

Luận văn được thực hiện với mục tiêu nhằm xác định được kiểu gen của virus viêm gan B ở một số bệnh nhân nhiễm virus tại Thái Nguyên bằng phương pháp PCR lồng (Nested - PCR). Mời các bạn cùng tham khảo.

63p zhangyan 13-07-2021 38 6   Download

Evaluate plasma microRNA-21 and microRNA-122 expression levels in hepatitis B virus-related hepatocellular carcinoma patients. Analyze the relationship between microRNA-21, microRNA-122 plasma with some clinical, subclinical and stage indicators in hepatitis B virus-related hepatocellular carcinoma patients.

27p gaocaolon7 18-09-2020 24 2   Download

Hepatitis B Infection is an occupational high risk factor. Immune response for vaccination was measured by Antibody to Hepatitis B surface antigen (anti HBs) levels. A course of Hep B vaccine yields a protective immune response (anti-HBs ≥10 mIU/mL) this study was designed to determine the anti HBs levels in Health Care Workers (HCWs) working as laboratory technician and staff nurses.

7p angicungduoc6 22-07-2020 24 3   Download

Luận văn Thạc sĩ Sinh học: Xây dựng quy trình phát hiện đột biến rtA181V/T và rtN236T kháng Adefovir của Virus viêm gan B (Hepatitis B Virus) bằng kỹ thuật Real Time PCR xây dựng quy trình xác định các đột biến kháng thuốc Adefovir của HBV tại rtA181V/T và rtN236T bằng kỹ thuật real-time PCR sử dụng TaqMan probe, chi phí thấp để phát triển thành kit phục vụ quá trình điều trị viêm gan siêu vi B trong tương lai.

99p maiyeumaiyeu05 20-08-2016 129 22   Download

Khoảng một phần ba dân số thế giới, tương ứng với 2 tỷ người, có tiền sử (đã từng bị) nhiễm vi rút viêm gan B, HBV: hepatitis B virus.

6p secrets_1 23-08-2013 68 3   Download

Human hepatitis delta (HDV) ribozyme is one of small ribozymes, such as hammerhead and hairpin ribozymes, etc. Its secondary structure shows pseudoknot structure com-posed of four stems (I to IV) and three single-stranded regions (SSrA, -B and -C). The 3D structure of 3¢-cleaved product of genomic HDV ribozyme provided extensive information about tertiary hydrogen bonding interactions between nucleotide bases, phosphate oxygens and 2¢OHs including new stem structure P1.1.

12p tumor12 22-04-2013 39 3   Download

Although efficient vaccines are available, chronic hepatitis B (HBV) infection poses a major health problem worldwide, and prolonged treatment of chronicallyinfected HBV patients with nucleoside analogs often results in drug-resistantHBVvariants.Therefore, it is critical toevaluate the contribution of the HBV polymerase to mutations. FLAG-taggedwild-type (FPolE) andmutant (FPolE/D551A)HBV polymerases have been expressed in insect cells and purified. The purified FPolE showed DNA polymerase activity, but FPolE/D551A did not, implying that the activity was derived from FPolE....

8p fptmusic 16-04-2013 41 3   Download

The humanSUV3gene encodes an NTP-dependent DNA⁄RNA DExH box helicase predominantly localized in mitochondria. Its orthologue in yeast is a component of the mitochondrial degradosome complex involved in the mtRNA decay pathway. In contrast to this, the physiological func-tion of human SUV3remains to be elucidated. In this report we demon-strate that the hSuv3 protein interacts with HBXIP, previously identified as a cofactor of survivin in suppression of apoptosis and as a protein that binds the HBx protein encoded by the hepatitis B virus....

12p fptmusic 12-04-2013 39 3   Download

A bio-nanocapsule (BNC), composed of the surface antigen (sAg) of the hepatitis B virus, is an efficient nanomachine with which to accomplish the liver-specific delivery of genes and drugs. Approximately 110 molecules of sAg are associated to form a BNC particle with an average diameter of 130 nm. TheLprotein is an sAg peptide composed mainly of preS and S regions. The preS region, with specific affinity for human hepatocytes, is localized in the N-terminus.

10p fptmusic 11-04-2013 37 2   Download

Toll-like receptors and RNA helicase family members [retinoic acid-inducible gene I (RIG-I) and melanoma differentiation associated gene-5 (MDA5)] play important roles in the induction of interferon-bas a major event in innate immune responses after virus infection. TRIF (adaptor pro-tein of Toll-like receptor 3)-mediated and Cardif (adaptor protein of RIG-I or MDA5)-mediated signaling pathways contribute rapid induction of interferon-bthrough the activation of interferon regulatory factor-3 (IRF-3)....

16p media19 04-03-2013 39 3   Download

We previously developed the bio-nanocapsule, which consists of hepatitis B virus envelope L proteins. The bio-nanocapsule can be used to deliver genes and drugs specifically to the human liver-derived tissues in xenograft models, presumably by utilizing the human liver-specific mechanism of hepatitis B virus infection.

11p vinaphone15 28-02-2013 34 2   Download

The betulinic acid (BetA) purified fromPulsatilla chinensis(PC) has been found to have selective inhibitory effects on hepatitis B virus (HBV). In hepatocytes from HBV-transgenic mice, we showed that BetA substantially inhibited HBV replication by downregulation of manganese superoxide dismutase (SOD2) expression, with subsequent reactive oxygen species gen-eration and mitochondrial dysfunction.

16p viettel02 22-02-2013 48 5   Download

Hepatitis B virus (HBV) is a 3.2 kb DNA virus that preferentially repli-cates in the liver. A number of transcription factors, including nuclear receptors, regulate the activities of HBV promoters and enhancers. How-ever, the association between these metabolic events and HBV replication remains to be clearly elucidated.

12p mobifone23 21-01-2013 44 5   Download

Hepatitis B virus (HBV) transcripts are subjected to multiple splicing deci-sions, but the mechanism of splicing regulation remains poorly understood. In this study, we used a well-investigated alternative splicing reporter to dissect splicing regulatory elements residing in the post-transcriptional reg-ulatory element (PRE) of HBV.

14p cosis54 05-01-2013 61 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Hepatitis C (HCV), hepatitis B (HBV), the human immunodeficiency viruses (HIV), and other viruses that replicate via RNA intermediaries,

14p dauphong6 05-01-2012 75 8   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Hepatitis B virus genotypes and precore and core mutants in UAE patients

8p dauphong3 26-12-2011 64 5   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Anti-hepatitis B core antigen testing with detection and characterization of occult hepatitis B virus by an in-house nucleic acid testing among blood donors in Behrampur, Ganjam, Orissa in southeastern India: implications for transfusion

7p dauphong3 26-12-2011 62 5   Download