Impairment

This research is designed to explore the difficulties in teaching and learning English as a foreign language to blind and low vision students at School X through teacher and students‟ self- reported difficulties they encountered in teaching and learning English.

84p closefriend09 16-11-2021 20 3   Download

Objectives of the study: First of all, the study aims to explore what motivate students with visual impairment to learn L2 before and after they enter the University. Secondly, it is to investigate what factors impact on their L2 learning motivation.

115p closefriend09 16-11-2021 25 4   Download

On the basis of theoretical and the real situation research of management in evaluation of professional competency of ToELVIs, this dissertation proposes measures to improve the quality of management in evaluation of professional competency of teachers teaching those students.

33p gaocaolon12 18-06-2021 32 3   Download

Research goal: The research proposes a number of measures on the development of listening and speaking skills for children with hearing impairment aged 3-6 years in inclusive kindergarten classes so as to facilitate their communication, language development according to age groups, and integration.

30p extraenglish 26-05-2021 26 3   Download

In this dissertation, we aim to propose a robust 3-D object detection and recognition system. As a feasible solution to deploy a real application, the proposed framework should be simple, robust and friendly to the VIPs.

28p gaocaolon6 30-07-2020 33 4   Download

Doctoral dissertation present the content: point cloud representation and the proposed method for table plane detection; primitive shapes estimation by a new robust estimator using geometrical constraints; detection and estimation of a 3-D object model for a real application; conclusion and future works.

159p gaocaolon6 30-07-2020 28 3   Download

The thesis evaluated the safety and improvement of spermatogenesis of Y10 capsules in experimental animals; Effect of improving the fertility of capsules Y10 in patients with impaired sperm.

26p angicungduoc6 21-07-2020 24 3   Download

The new conclusions of this study: Speckle tracking echocardiography can detect significant left ventricular impairment in patients with septic shock, which was not otherwise detectable by conventional echocardiography.

27p slimzslimz 21-12-2019 63 9   Download

This topic is researched for two goals: Study clinical characteristics, target organ lesions, glucose tolerance test results and insulin resistance in patients with new hypertension associated with impaired fasting glucose. Evaluate the relationship between insulin resistance and target organ lesions in patients with new hypertension associated with impaired fasting glucose.ư

27p slimzslimz 21-12-2019 32 7   Download

Department of Medical Biochemistry and Biology, University of Bari, Italy; 2Department of Zoology, Laboratory of Histology and Comparative Anatomy, University of Bari, Italy; 3Center for the Study of Mitochondria and Energy Metabolism (CNR) Bari, Italy Mitochondrial bioenergetic impairment has been found in the organelles isolated from rat liver during the prereplicative phase of liver regeneration.

9p system191 01-06-2013 35 4   Download

Mitochondrial functional and structural impairment and generation of oxidative stress have been implicated in aging, various diseases and chemotherapies. This study analyzed azidothymidine (AZT)-caused failures in mitochondrial functions, in redox regulation and activation of the HIV-1 gene expression. We monitored intracellular concentrations of ATP and glutathione (GSH) as the indicators of energy production and redox conditions, respectively, during the time-course experiments with U937 and MOLT4 human lymphoid cells in the presence of AZT (0.05 mgÆmL)1) or H2O2 (0.01 mM) for 15–25 days.

7p system191 01-06-2013 42 3   Download

DNA transactions in eukaryotes require that proteins gain access to target sequences packaged in chromatin. Further, interactions between distinct nucleoprotein complexes are often required to generate higher-order structures. Here, we employed two prokaryotic site-specific recombination systems to investigate how chromatin packaging affects the assembly of nucleoprotein structures of different complexities at more than 30 genomic loci. The dynamic nature of chromatin permitted protein–DNA and DNA–DNA interactions for sites of at least 34 bp in length.

7p system191 01-06-2013 50 4   Download

Matrix metalloproteinase (MMP)-3 inhibited human MDA-MB-231 breast cancer cell invasion through recon-stituted basement membranein vitro. Inhibition of invasion was dependent upon plasminogen and MMP-3 activation, was impaired by the peptide MMP-3 inhibitor Ac-Arg-Cys-Gly-Val-Pro-Asp-NH2 and was associated with: rapid MMP-3-mediated plasminogen degradation to microplas-minogen and angiostatin-like fragments;

8p research12 23-04-2013 35 3   Download

Protein synthesis requires both amino acids, as precursors, and a substantial amount of metabolic energy. It is well established that starvation or lack of nutrients impairs pro-tein synthesis in mammalian cells and tissues. Branched chain amino acids are particularly effective in promoting protein synthesis. Recent work has revealed important new information about the mechanisms involved in these effects. Anumber of components of the translational machinery are regulated through signalling events that require the mam-malian target of rapamycin, mTOR. ...

12p tumor12 22-04-2013 34 2   Download

The nonphotosynthetic mutant ofArabidopsis hcf152is impaired in the processing of the chloroplast polycistronic transcript, psbB-psbT-psbH-petB-petD, resulting in non-production of the essential photosynthetic cytochromeb6 f complex. The nucleus-encodedHCF152gene was identified to encode a pentatricopeptide repeat (PPR) protein com-posed primarily of 12 PPR motifs, similar to other proteins of this family that were identified in mutants defected in chloroplast gene expression.

12p tumor12 20-04-2013 32 2   Download

Synaptophysin, one of the major proteins on synaptic vesi-cles, is ubiquitously expressed throughout the brain. Syn-aptophysin and synapsin I, another synaptic vesicle protein, are also expressed by retinoic acid-induced neuronally dif-ferentiated P19 teratocarcinoma cells. Here, we show that inhibition of histone deacetylase activity in P19 cells is suf-ficient to activate transcription of the synaptophysin and synapsin I genes, indicating that neuronal differentiation and impairment of histone deacetylases results in a similar gene expression pattern....

8p tumor12 20-04-2013 29 1   Download

Activation of a temperature-sensitive formof p53 inmurine erythroleukaemia cells results in a rapid impairment of protein synthesis that precedes inhibitionof cell proliferation and loss of cell viability by several hours. The inhibition of translation is associated with specific cleavages of polypep-tide chain initiation factors eIF4GI and eIF4B, a pheno-menon previously observed in cells induced to undergo apoptosis in response to other stimuli.

11p fptmusic 16-04-2013 33 3   Download

The induction of the heat shock response as well as its termination is auto-regulated by heat shock protein activities. In this study we have investi-gated whether Hsp90 functional protein levels influence the characteristics and duration of the heat shock response. Treatment of cells with several benzoquinone ansamycin inhibitors of Hsp90 (geldanamycin, herbimycin A) activated a heat shock response in the absence of heat shock, as reported previously.

13p fptmusic 12-04-2013 50 3   Download

Alterations in mitochondrial activity resulting from defects in mitochond-rial DNA (mtDNA) can modulate the biogenesis of mitochondria by mech-anisms that are still poorly understood. In order to study mitochondrial biogenesis in cells with impaired mitochondrial activity, we used rho-L929 and rho 0 143 B cells (partially and totally depleted of mtDNA, respectively),

25p fptmusic 12-04-2013 56 4   Download

Aspergillus fumigatusis responsible for many allergic respiratory diseases, the most notable of which )due to its severity)is allergic bronchopulmo-nary aspergillosis. Aspf1 is a major allergen of this fungus: this 149-amino acid protein belongs to the ribotoxin family, whose best characterized member isa-sarcin (EC 3.1.27.10). The proteins of this group are cytotoxic ribonucleases that degrade a unique bond in ribosomal RNA impairing protein biosynthesis.

9p awards 06-04-2013 37 3   Download