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T lymphocytes
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Although immune cell therapy has long been used for treating solid cancer, its efficacy remains limited. Interferon (IFN)-producing killer dendritic cells (IKDCs) exhibit cytotoxicity and present antigens to relevant cells; thus, they can selectively induce tumor-associated antigen (TAA)-specific CD8 T cells and may be useful in cancer treatment.
12p
vishanshan
27-06-2024
2
1
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Different from other resources, this volume offers a broad appeal to microbiologists, immunologists, and infectious disease specialists on Autoimmune Diseases. The volume covers topics such as skin and alopecia, Kidney, Liver, Paraneoplastic, Resolution of inflammation, Cardiovascular/systemic inflammation and atherosclerosis, Gut, Regulatory lymphocytes T, B, other and Rheumatic Disease. The volume is written by internationally renowned authors who are authorities in their respective fields.
1327p
vimeyers
29-05-2024
2
2
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The IRE1a-XBP1 pathway is a conserved adaptive mediator of the unfolded protein response. The pathway is indispensable for the development of secretory cells by facilitating protein folding and enhancing secretory capacity.
19p
vibransone
28-03-2024
5
2
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Neoantigens that arise as a consequence of tumor-specific mutations can be recognized by T lymphocytes leading to effective immune surveillance. In colorectal cancer (CRC) and other tumor types, a high number of neoantigens is associated with patient response to immune therapies.
22p
vibransone
28-03-2024
4
2
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The efficacy of checkpoint blockade immunotherapies in colorectal cancer is currently restricted to a minority of patients diagnosed with mismatch repair-deficient tumors having high mutation burden. However, this observation does not exclude the existence of neoantigen-specific T cells in colorectal cancers with low mutation burden and the exploitation of their anti-cancer potential for immunotherapy.
15p
vibransone
28-03-2024
2
2
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Immune checkpoint blockade (ICB) with antibodies inhibiting cytotoxic T lymphocyte-associated protein-4 (CTLA-4) and programmed cell death protein-1 (PD-1) (or its ligand (PD-L1)) can stimulate immune responses against cancer and have revolutionized the treatment of tumors.
13p
vibransone
28-03-2024
7
2
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Systemic sclerosis (SSc) is a genetically complex autoimmune disease mediated by the interplay between genetic and epigenetic factors in a multitude of immune cells, with CD4+ T lymphocytes as one of the principle drivers of pathogenesis.
17p
vibransone
28-03-2024
3
2
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The T cell-inflamed tumor microenvironment, characterized by CD8 T cells and type I/II interferon transcripts, is an important cancer immunotherapy biomarker. Tumor mutational burden (TMB) may also dictate response, and some oncogenes (i.e., WNT/β-catenin) are known to mediate immunosuppression.
19p
vibransone
28-03-2024
3
2
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Truyền lympho T người cho (Donor lymphocyte infusion – DLI) là một dạng của liệu pháp miễn dịch làm tăng cường hiệu ứng mảnh ghép chống ung thư (Graft-versus-leukemia – GVL) nhằm duy trì tình trạng lui bệnh lâu dài sau dị ghép tế bào gốc tạo máu (TBGTM). Bài viết trình bày bước đầu ứng dụng truyền tế bào lympho người cho trong dị ghép tế bào gốc tạo máu.
6p
virichard
28-03-2024
4
2
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Ebook "Cell death: Mechanism and disease" provides a comprehensive view of cell death, from its mechanisms of initiation and execution, to its implication in human disease and therapy. Physiological cell death plays critical roles in almost all aspects of biology, and the book details its roles in lymphocyte homeostasis, neuronal function, metabolism, and the DNA damage response. When physiological cell death goes awry, diseases can arise, and cancer is presented as a central paradigm for the consequences of derangements in the interplay between cell survival and cell death.
280p
manmanthanhla0201
26-02-2024
2
1
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Mononeuritis multiplex is a rare autoimmune peripheral neuropathy that typically presents in the context of vasculitis, diabetes, infection, or as a paraneoplastic syndrome. Adverse immune-related neurological conditions have been increasingly reported with the use of immune checkpoint inhibitors against cytotoxic T-lymphocyte antigen-4 and/or the programmed cell death protein 1/programmed death ligand-1 axis.
5p
vitiki
30-01-2024
8
2
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Ebook "The biology of dendritic cells and HIV infection" focuses on the role of DCs in the pathogenesis and immunity of HIV-1 infection. It has recently been clarified that DCs are important targets and reservoirs of HIV and may play an important role in virus spreading to T cells. Interestingly, HIV can exploit many of the cellular processes responsible for the generation and regulation of the adaptive immune responses to gain access to its main target cells, i.e. the CD4+ T lymphocytes.
562p
tachieuhoa
28-01-2024
3
2
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Part 1 book "Veterinary immunology" includes content: Surviving in a microbial world; innate immunity; humoral innate immunity; humoral innate immunity; cellular innate immunity; cellular innate immunity; sickness; how immune cells communicate; antigens; dendritic cells and antigen processing; the major histocompatibility complex; organs of the immune system; lymphocytes; helper t-cells and their response to antigens; b-cells and their response to antigens; antibodies.
504p
muasambanhan03
02-01-2024
9
2
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Part 1 book "Veterinary immunology" includes content: The defense of the body, innate immunity, innate immunity, innate immunity, innate immunity, systemic responses to inflammation; innate immunity; cell signaling; antigens; dendritic cells and antigen processing; the major histocompatibility complex; organs of the immune system; lymphocytes; helper t'cells and their response to antigen; b'cells and their response to antigen 16 antibodies; how antigen binding receptors are made,... and other contents.
324p
muasambanhan03
02-01-2024
2
2
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Relationship between cancer cell glycolysis and the landscape of tumor immune microenvironment in human cancers was investigated. Forty-one fresh lung adenocarcinoma (ADC) tissues were analyzed using flow cytometry for comprehensive immunoprotein. Formalin-fixed tissues were immunostained for hexokinase-2 (HK2) to assess cancer cell glycolysis.
11p
vileonardodavinci
23-12-2023
5
3
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To investigate the expression of programmed death ligand-1 (PD-L1) and the levels of CD8+ tumor-infiltrating lymphocytes (TILs) in meningioma as well as determine the association between their levels and the clinical outcomes.
11p
vileonardodavinci
23-12-2023
3
2
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Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) and T cell/histiocyte-rich large B-cell lymphoma (THRLBCL) have overlapping histological features that make their diagnosis challenging. Insulin-like growth factor II mRNA-binding protein 3 (IMP3) is a recently proposed diagnostic marker for Hodgkin’s lymphoma.
10p
vileonardodavinci
23-12-2023
4
2
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While immune checkpoint inhibitors (ICIs) occasionally cause immune-related adverse events (irAEs) in various organs, the prevalence of irAEs and potential risk factors have not been clarified. We identified irAE predictive factors and examined the relationship between the effect of ICIs and irAEs for patients with malignancies.
9p
vileonardodavinci
23-12-2023
4
2
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The distribution of tissue-inflating lymphocytes has been shown to affect the prognosis of patients with pancreatic cancer in some previous studies. However, the role of peripheral lymphocytes in pancreatic cancer remains debated. The purpose of this study was to analyze the peripheral subtypes of T lymphocytes, and establish their association with the prognosis of patients with pancreatic cancer.
14p
vileonardodavinci
23-12-2023
9
3
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Less than half of unselected metastatic cancer patients benefit from the immune checkpoint inhibitor (ICI) therapy. Systemic cancer-related inflammation may influence the efficacy of ICIs and thus, systemic inflammatory markers could have prognostic and/or predictive potential in ICI therapy.
11p
vileonardodavinci
23-12-2023
4
2
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