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Báo cáo khoa học: Conserved residues in the N-domain of the AAA+ chaperone ClpA regulate substrate recognition and unfolding
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Protein degradation in the cytosol ofEscherichia coliis carried out by a variety of different proteolytic machines, including ClpAP. The ClpA com-ponent is a hexameric AAA+ (ATPase associated with various cellular activities) chaperone that utilizes the energy of ATP to control substrate recognition and unfolding.
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