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G protein
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G-quadruplex (G4) là acid nucleic có cấu trúc bậc hai được hình thành bởi các trình tự giàu guanine. G4 hiện diện phổ biến trong tất cả các bản phiên mã và bộ gen của sinh vật. Bài viết tập trung thảo luận về những ứng dụng của tương tác đặc hiệu giữa peptide RHAU và G4 song song trong những phản ứng sinh hóa.
11p
vithomson
02-07-2024
0
0
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The primary aim of Cerebral Signal Transduction: From First to Fourth Messengers, therefore, is to offer a comprehensive picture of the recent advances made in the signaling field as it relates to neuronal and cere bral function. The current state of progress provides an exciting opportunity for such a comprehensive focus because molecular tools have become available to selectively remove, reduce, or enhance spe cific components in the signaling pathways, e. g. , by interfering with the genes encoding key proteins.
441p
vimeyers
29-05-2024
3
2
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Ebook "Lymphangiogenesis in cancer metastasis" covers all aspects of this new field from the fundamental role that protein growth factors and their receptors play in lymphangiogenesis to the potential application of these advances to cancer diagnosis and treatment. Other clinical aspects explored include the mechanisms and importance of lymph node metastasis, the role of the lymphatics in lymphangioleiomyomatosis and Kaposi’s sarcoma, and approaches for imaging lymphatics in cancer.
254p
dongmelo
27-05-2024
6
2
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Ebook "Cell polarity 2: Role in development and disease" provides a state-of-the art overview on the most relevant aspects of cell polarity. Volume 2 discusses the physiological and pathophysiological relevance of cell polarity. It especially focuses on pathophysiological conditions in which one or several aspects of cell polarity are impaired, and in which a loss of cell polarity possibly contributes to disease (e.g. epithelial-to-mesenchymal transition in cancer, role of polarity proteins in cancer).
228p
ladongphongthanh1008
22-04-2024
2
1
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Ebook "CtBP family proteins" are unique in several aspects. They were the first among proteins containing a metabolic enzyme fold to be implicated in transcriptional regulation. The vertebrate CtBPs exhibit distinct nuclear and cytosolic activities. The crystal struaures of CtBPl and molecular modeling studies have illuminated the molecular basis of its dual activity and the interaction with target peptides.
131p
ladongphongthanh1008
22-04-2024
5
2
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Ebook "Ras superfamily small G proteins: Biology and mechanisms 2 (Transport)" discusses subfamily proteins which function in molecular and vesicular transport mechanisms inside the cell. In this volume the focus lies on the Rab, Ran and Arf subfamily members. As in Volume 1, the book is written by international renowned scientists in the field of small G-proteins. In elaborate reviews, biochemistry, structure, function and G-protein - effector interactions are described. Together with Volume 1 this book provides an comprehensive state-of-the-art work on small G-proteins (GTPases).
299p
tracanhphuonghoa1007
22-04-2024
2
2
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Ebook "Chemistry of maillard reactions in processed foods" s aim at presenting chemical background information or an introduction and clear-cut overview on the chemistry related to specific topics in this area. Typical topics thus include: ccompound classes in foods—their chemistry and properties with respect to the foods (e.g. sugars, proteins, fats, minerals,...); contaminants and additives in foods—their chemistry and chemical transformations;...
64p
tracanhphuonghoa1007
22-04-2024
7
3
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Ebook "Sweeteners: Pharmacology, biotechnology, and applications" introduces various substance classes of sweeteners, which are mainly plant-derived, including glycosidic and terpenoid sweeteners, peptidic sweeteners, sweet-tasting proteins and protein-derived sweeteners (e.g. stevioside, sucralose, aspartame, thaumatin, brazzein and many more).
652p
tracanhphuonghoa1007
22-04-2024
4
3
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Ebook "Chemical evolution of nitrogen-based compounds in mozzarella cheeses" summarizes how the presence of amines is influenced by different factors such as cheese variety, seasoning and microflora. The authors compare typical profiles of different products, e.g. ripe vs. unripe cheeses, focusing also on the different types of mozzarella cheeses. The Brief also introduces several analytical methods and simulation techniques, which are being used to evaluate the evolutive profiles of different selected molecules, protein aggregation, or proteolysis.
48p
tracanhphuonghoa1007
22-04-2024
3
2
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In ebook "Molecular computing: Origins and promises" an attempt was made to tell about the formation and development of the research on molecular devices of information processing that took place in the atmosphere full of hopes, enthusiasm, successes, and disappointments. It seems to me that it is necessary to write about this now, when there appeared a real possibility to create fundamentally new computing and information-logical devices on the molecular level.
228p
tudohanhtau1006
29-03-2024
4
1
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Ebook "Chemokines: Chemokines and their receptors in drug discovery" covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level,...
248p
tudohanhtau1006
29-03-2024
1
1
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Ebook "Proteomics in foods: Principles and applications" will discuss recent developments and the expected trends of the near future in food proteomics. The book will be divided into two parts. The first part (7 chapters) will focus on the basic principles for proteomics, e.g., sample preparation, such as extraction and separation techniques, analytical instrumentation currently in use, and available databases for peptide and protein identification.
589p
coduathanh1122
27-03-2024
3
1
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Ebook "SUMO regulation of cellular processes (Second edition)" of a very well received book that details how the sumoylation system functions and how it modulates numerous cellular activities. SUMO is a post-translational modifier in the ubiquitin super-family that has gained recognition over the last twenty years as an essential and prevalent regulatory molecule. Individual chapters explore the biochemistry, molecular biology, and cell biology of the sumoylation system and its substrate proteins.
413p
cotieubac1004
15-03-2024
1
0
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Ebook "RAMPs (Advances in experimental medicine and biology, Volume 744)" provides a general introduction to RAMPs including its discovery. The second chapter (by Poyner and colleagues) and the third chapter (by Bomberger and colleagues) are intended to provide in depth discussion on how the different RAMP isoforms can regulate various aspects of receptor signaling especially stimulated with calcitonin gene related peptide (CGRP) and adrenomedullin. In addition, in the third chapter, Bomberger et al discuss the differences in RAMP2 and -3 with regard to their role in receptor trafficking.
126p
cotieubac1004
15-03-2024
2
0
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Ebook "Biocompatible graphene for bioanalytical applications" highlights the latest advances in the use of graphene and bio-compatible-material-decorated graphene to detect various targets (e.g. DNA, RNA, amino acids, peptides, proteins, enzymes, antigens, glucose, DA, AA, UA, ATP, NADH, gas, ions, etc.). It focuses on the specific interaction of these substances with graphene (or modified graphene) and the efficient transduction of the target recognition event into detectable signals via various techniques.
122p
nhanphanguyet
28-01-2024
4
2
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Ebook "G protein-coupled receptors - Modeling and simulation" which provides, for the first time, state-of-the-art views on modeling and simulation of GPCRs, is divided into 4 parts. In the first part, the impact of currently available GPCR crystal structures on structural modeling is discussed extensively as are critical insights from simulations in the second part of the book. The third part reports recent progress in rational ligand discovery and mathematical modeling, whereas the fourth part provides an overview of bioinformatics tools and resources that are available for GPCRs.
228p
nhanphanguyet
28-01-2024
5
2
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Ebook "Inhibitory regulation of excitatory neurotransmission" reviews aspects of GABAA receptor function, as well as the properties of a variety of other important inhibitory proteins, such as GABAC receptors, G-protein coupled receptors (specifically, GABAB receptors, metabotropic glutamate receptors and neuropeptide receptors), glycine receptors, GABA transporters and potassium channels.
256p
tachieuhoa
28-01-2024
4
2
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Ebook "Computational methods for GPCR drug discovery" looks at modern computational strategies and techniques used in GPCR drug discovery including structure and ligand-based approaches and cheminformatics.
437p
lamquandat
28-12-2023
6
2
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Ebook "Advanced technologies for managing insect pests" among the highlights of this book is the use of novel insecticides acting on a specific site in an insect group and are compatible with natural enemies and the environment. One of such approaches is based on disrupting the activity of biochemical sites acting on transcription factors such as the Helix-Loop-Helix (bHLH) family, anti juvenile hormone (AJH) agents that target JH biosynthetic enzymes, G-protein coupled receptors (GPCR) and bursicon as a target for insect control.
331p
lamquandat
28-12-2023
4
2
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The aim of this study was to sequence fulllength p72 gene of a field strain of ASFV causing typical ASF in Dong Nai province in 2020 and fuse this p72 gene with VSV G gene to generate a recombinant fusion gene G-p72 that could simultaneously express both proteins and stimulate a better host immune response than p72 expression alone.
10p
vimichaelfaraday
28-12-2023
7
3
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