Cells
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The process of neural stem cell (NSC) differentiation into neurons is crucial for the development of potential cell-centered treatments for central nervous system disorders. However, predicting, identifying, and anticipating this differentiation is complex. In this study, we propose the implementation of a convolutional neural network model for the predictable recognition of NSC fate, utilizing single-cell brightfield images.
7p vithomson 02-07-2024 0 0 Download
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Part 1 book "Neural stem cells and cellular therapy" includes content: Introduction adult neural stem cells - the promise of the future, neurogenesis in the adult central nervous system, BrdU immunohistochemistry for studying adult neurogenesis - paradigms, pitfalls, limitations and validation; adult neural stem cells, neurogenic niches and cellular therapy;... and other contents.
124p dianmotminh04 12-07-2024 0 0 Download
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Part 1 book "Neural stem cells and cellular therapy" includes content: Adult neurogenesis pharmacology in neurological diseases and disorders, adult neural stem cells - A promising candidate for regenerative therapy in the CNS; stem cells engineering for cell based therapy; therapeutic neuronal stem cells - patents at the forefront;... and other contents.
112p dianmotminh04 12-07-2024 0 0 Download
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Part 2 book "Protein-Carbohydrate interactions - Methods and protocols" includes content: Bioinspired assemblies of plant cell walls for measuring protein carbohydrate interactions by FRAP; CBMs as probes to explore plant cell wall heterogeneity using immunocytochemistry; determining the localization of carbohydrate active enzymes within gram negative bacteria,... and other contents.
138p dianmotminh04 12-07-2024 0 0 Download
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Part 1 book "The biochemistry of inorganic polyphosphates" includes content: The chemical structures and properties of condensedinorganic phosphates, methods of polyphosphate assay in biological materials, the occurrence of polyphosphates in living organisms, the forms in which polyphosphates are present in cells, localization of polyphosphates in cells of prokaryotesand eukaryotes, enzymes of polyphosphate biosynthesis and degradation.
106p dianmotminh04 12-07-2024 2 0 Download
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Carotenoids are a group of 40-carbon isoprenoids with high lipid solubility, widely found in fruits, vegetables, etc. They have an unsaturated structure with strong antioxidant activity that helps prevent low-density lipoprotein oxidation and protect cells from free radicals.
8p viwalton 02-07-2024 2 1 Download
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To estimate the rate of occult nodal metastases in patients with squamous carcinoma of the oral tongue in oral tongue cancer patients with clinical negative lymph nodes; To investigate the relationship between some clinicopathologic factors and the occult cervical nodal metastases in patients with oral tongue cancer.
5p vikoch 27-06-2024 1 1 Download
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This study aims to evaluate perioperative, oncological, and functional outcomes of laparoscopic partial nephrectomy performed for cT1bN0M0 renal cell carcinoma at Binh Dan Hospital. Data were collected on 37 patients who had undergone laparoscopic partial nephrectomy for cT1bN0M0 renal cell carcinoma from January 2021 to September 2023.
8p vikoch 27-06-2024 2 1 Download
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Cervical lymph node metastasis (LNM) is an important prognostic factor for patients with non-small cell lung cancer (NSCLC). We aimed to develop and validate machine learning models that use ultrasound radiomic and descriptive semantic features to diagnose cervical LNM in patients with NSCLC.
11p vishanshan 27-06-2024 1 1 Download
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Oesophageal squamous cell carcinoma is one of the most commonly diagnosed carcinomas in China, and postoperative radiotherapy plays an important role in improving the prognosis of patients. Carcinomas in different locations of the oesophagus could have different patterns of lymph node metastasis after surgery.
8p vishanshan 27-06-2024 2 1 Download
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Gastric cancer (GC) is one of the most prevalent malignant tumors worldwide and is associated with high morbidity and mortality rates. However, the specific biomarkers used to predict the postoperative prognosis of patients with gastric cancer remain unknown. Recent research has shown that the tumor microenvironment (TME) has an increasingly positive effect on anti-tumor activity. This study aims to build signatures to study the effect of certain genes on gastric cancer.
17p vishanshan 27-06-2024 1 1 Download
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In recent years, there has been an increase in the incidence and mortality rates of prostate cancer (PCa). However, the specific molecular mechanisms underlying its occurrence and development remain unclear, necessitating the identification of new therapeutic targets.
10p vishanshan 27-06-2024 2 1 Download
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Long nonconding RNAs (lncRNAs) have been found to be a vital regulatory factor in the development process of human cancer, and could regarded as diagnostic or prognostic biomarkers for human cancers. Here, we aim to confirm the expression and molecular mechanism of RP11-171K16.5 (lnc171) in hepatocellular carcinoma (HCC).
13p vishanshan 27-06-2024 1 1 Download
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Cervical cancer is the fourth most common cancer in women, with an estimated 342,000 deaths worldwide in 2020. Current standard of care in the UK for locally advanced cervical cancer is concurrent chemoradiotherapy with weekly cisplatin, yet 5-year overall survival rates are only 65% with a distant relapse rate of 50%.
10p vishanshan 27-06-2024 1 1 Download
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While radiation therapy remains pivotal in esophageal squamous cell carcinoma (ESCC) treatment, the perplexing phenomenon of post-radiation metastasis presents a formidable clinical challenge. This study investigates the role of fibrinogen-like protein 1 (FGL1) in driving ESCC metastasis following radiation exposure.
13p vishanshan 27-06-2024 2 1 Download
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In this study, we demonstrated that the expression of MUC1 was greater in neoplastic tissues than in non-neoplastic tissues of the cervix, and cervical squamous cell carcinoma patients with high MUC1 expression had significantly worse overall survival than did those with low MUC1 expression, indicating its potential for early diagnosis of cervical squamous cell carcinoma.
14p vishanshan 27-06-2024 1 1 Download
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No definite conclusion has yet to be reached for immunotherapy beyond progression(IBP) of first line immunotherapy as the second-line treatment for advanced NSCLC patients with negative driver genes. Therefore a retrospective study was conducted to evaluate the efficacy of IBP in this population and investigated whether the cycles best response and progressive mode of first-line immunotherapy could affect the results.
13p vishanshan 27-06-2024 1 1 Download
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YAP and TAZ, the Hippo pathway terminal transcriptional activators, are frequently upregulated in cancers. In tumor cells, they have been mainly associated with increased tumorigenesis controlling different aspects from cell cycle regulation, stemness, or resistance to chemotherapies.
18p vishanshan 27-06-2024 1 1 Download
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5-Fluorouracil (5FU) is a primary chemotherapeutic agent used to treat oral squamous cell carcinoma (OSCC). However, the development of drug resistance has significantly limited its clinical application. Therefore, there is an urgent need to determine the mechanisms underlying drug resistance and identify effective targets.
16p vishanshan 27-06-2024 2 1 Download
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Nowadays, different therapeutic options are available for the first-line treatment of metastatic renal cell carcinoma (mRCC). Immuno-combinations are the standard first-line therapy in all mRCC patients regardless of the International Metastatic RCC Database Consortium (IMDC) risk category, even though TKI monotherapy is still a therapeutic option in selected patients.
5p vishanshan 27-06-2024 2 1 Download